HitPredict

Interactor 1: PPIH (O43447)
Peptidyl-prolyl cis-trans isomerase H (PPIase H) (EC 5.2.1.8) (Rotamase H) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP)
Gene: PPIH

Interactor 2: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28515276, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016607 - nuclear speck GO:0043231 - intracellular membrane-bounded organelle and 1 others more... GO:0046540 - U4/U6 x U5 tri-snRNP complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 177 Hs			1 972
+	Hs
		614328 PPIB_HUMAN (3-177): 7e-87: 255: 53.71		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		1064837 PPIE_HUMAN (3-176): 2.17e-83: 249: 55.75		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		923688 PPIA_HUMAN (9-177): 2.81e-83: 244: 53.85		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		531109 PPIA_HUMAN (9-177): 2.81e-83: 244: 53.85		EF2_HUMAN (111-957): 0: 915: 38.16
+	Hs
		673714 PPIF_HUMAN (10-177): 5.05e-86: 253: 55.95		EFGM_HUMAN (107-932): 0: 585: 19.64