Protein: IF2B
Eukaryotic translation initiation factor 2 subunit beta (eIF2-beta)

Gene: IF2B, SUI3
Organism: Saccharomyces cerevisiae S288C
Interactions: 97
UniProt ID: P09064

Gene Ontology (top 5):
GO:0001731 - formation of translation preinitiation complex
GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0003729 - mRNA binding
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

447168

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

14

6

Small-scale

0.984

High

447174

SUI1
Eukaryotic translation initiation factor eIF-1

3

2

Small-scale

0.840

High

402843

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

2

1

High-throughput

0.802

High

447184

IF5
Eukaryotic translation initiation factor 5

12

8

Small-scale

0.760

High

447170

EI2BE
Translation initiation factor eIF2B subunit epsilon

12

4

Small-scale

0.758

High

447190

IF2P
Eukaryotic translation initiation factor 5B

2

4

Small-scale

0.754

High

446953

EI2BG
Translation initiation factor eIF2B subunit gamma

8

4

Small-scale

0.754

High

447154

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

8

6

Small-scale

0.747

High

447152

EI2BA
Translation initiation factor eIF2B subunit alpha

5

7

Small-scale

0.714

High

447171

EI2BB
Translation initiation factor eIF2B subunit beta

5

7

Small-scale

0.714

High

410051

EIF3B
Eukaryotic translation initiation factor 3 subunit B

4

3

Small-scale

0.683

High

447181

EIF3A
Eukaryotic translation initiation factor 3 subunit A

3

3

Small-scale

0.662

High

447148

EI2BD
Translation initiation factor eIF2B subunit delta

3

7

Small-scale

0.646

High

447169

EIF3C
Eukaryotic translation initiation factor 3 subunit C

3

3

Small-scale

0.642

High

447172

PP12
Serine/threonine-protein phosphatase PP1-2

3

0

High-throughput

0.638

High

447180

HEK2
Heterogeneous nuclear rnp K-like protein 2

2

1

High-throughput

0.621

High

447205

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.618

High

447155

IF5A1
Eukaryotic translation initiation factor 5A-1

2

0

Small-scale

0.559

High

447199

BRE5
UBP3-associated protein BRE5

1

2

High-throughput

0.536

High

447204

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

447163

NSR1
Nuclear localization sequence-binding protein

1

2

High-throughput

0.515

High

447191

FKH1
Fork head protein homolog 1

1

0

High-throughput

0.513

High

412620

KAPA
cAMP-dependent protein kinase type 1

1

4

Small-scale

0.501

High

447139

IF2B
Eukaryotic translation initiation factor 2 subunit beta

1

3

Small-scale

0.501

High

447207

PKH1
Serine/threonine-protein kinase PKH1

1

4

Small-scale

0.501

High

447165

XPO1
Exportin-1

1

5

High-throughput

0.489

High

447153

GCN2
eIF-2-alpha kinase GCN2

1

0

Small-scale

0.480

High

141067

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

357610

RL28
Large ribosomal subunit protein uL15

1

1

High-throughput

0.479

High

382864

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.479

High

405338

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.479

High

406668

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

407632

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

408217

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

1

High-throughput

0.479

High

413216

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.479

High

425670

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.479

High

447140

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.479

High

447141

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.479

High

447142

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.479

High

447143

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.479

High

447144

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

447149

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.479

High

447151

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

447156

SIS1
Protein SIS1

1

3

High-throughput

0.479

High

447157

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

447160

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.479

High

447161

RL16A
Large ribosomal subunit protein uL13A

1

3

High-throughput

0.479

High

447162

RS7A
Small ribosomal subunit protein eS7A

1

3

High-throughput

0.479

High

447164

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

447166

HS104
Heat shock protein 104

1

3

High-throughput

0.479

High

447173

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.479

High

447175

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.479

High

447177

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

447178

GBLP
Small ribosomal subunit protein RACK1

1

5

High-throughput

0.479

High

447185

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

447188

DHH1
ATP-dependent RNA helicase DHH1

1

2

High-throughput

0.479

High

447189

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

447194

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

5

High-throughput

0.479

High

447198

RL26B
Large ribosomal subunit protein uL24B

1

2

High-throughput

0.479

High

447201

GIS2
Zinc finger protein GIS2

1

2

High-throughput

0.479

High

447208

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

447214

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.479

High

357792

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

405922

RL33A
Large ribosomal subunit protein eL33A

1

0

High-throughput

0.458

High

447150

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.458

High

447176

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

Small-scale

0.458

High

447186

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

447196

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

447215

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

447147

SCH9
Serine/threonine-protein kinase SCH9

1

4

Small-scale

0.457

High

365608

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

447145

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

447146

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

447158

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

447179

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

447206

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.437

High

447210

CD123
Translation initiation factor eIF2 assembly protein

1

2

Small-scale

0.437

High

350757

RAS1
Ras-like protein 1

1

2

High-throughput

0.407

High

447200

IST1
Vacuolar protein sorting-associated protein IST1

2

0

High-throughput

0.307

High

399273

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.249

Low

447159

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

447167

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

447182

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.249

Low

447183

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

447192

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

447193

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

447195

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

447197

GNP1
High-affinity glutamine permease

1

0

High-throughput

0.249

Low

447202

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

447209

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.249

Low

447211

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

447212

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

447213

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

447216

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low

447187

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.232

Low

447203

H3
Histone H3

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024