HitPredict - High confidence protein-protein interactions

Interactor 1: ATIF1 (O35143)
ATPase inhibitor, mitochondrial (ATP synthase F1 subunit epsilon) (Inhibitor of F(1)F(o)-ATPase) (IF(1)) (IF1)
Gene: Atp5if1

Interactor 2: ATIF1 (O35143)
ATPase inhibitor, mitochondrial (ATP synthase F1 subunit epsilon) (Inhibitor of F(1)F(o)-ATPase) (IF(1)) (IF1)
Gene: Atp5if1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	29199018, 29222160, 28130547
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	IATP~IATP
Common GO terms	GO:0001937 - negative regulation of endothelial cell proliferation GO:0005516 - calmodulin binding GO:0005739 - mitochondrion GO:0006783 - heme biosynthetic process GO:0009986 - cell surface and 14 others more... GO:0030218 - erythrocyte differentiation GO:0032991 - protein-containing complex GO:0042030 - ATPase inhibitor activity GO:0043532 - angiostatin binding GO:0051117 - ATPase binding GO:0051346 - negative regulation of hydrolase activity GO:0051882 - mitochondrial depolarization GO:0072593 - reactive oxygen species metabolic process GO:0140260 - mitochondrial proton-transporting ATP synthase complex binding GO:1901030 - positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1903052 - positive regulation of proteolysis involved in protein catabolic process GO:1903214 - regulation of protein targeting to mitochondrion GO:1905091 - positive regulation of type 2 mitophagy GO:1905707 - negative regulation of mitochondrial ATP synthesis coupled proton transport
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	106
Mm

1	106

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Last updated: 11Aug2025