Protein: ATIF1
ATPase inhibitor, mitochondrial (ATP synthase F1 subunit epsilon) (Inhibitor of F(1)F(o)-ATPase) (IF(1)) (IF1)

Gene: ATIF1, ATP5IF1
Organism: Homo sapiens
Interactions: 185
UniProt ID: Q9UII2

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001937 - negative regulation of endothelial cell proliferation
GO:0004857 - enzyme inhibitor activity
GO:0005516 - calmodulin binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

444015

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

6

3

High-throughput

0.943

High

784760

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

2

1

High-throughput

0.811

High

680537

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

2

3

Small-scale

0.789

High

1414979

CP250
Centrosome-associated protein CEP250

5

1

High-throughput

0.706

High

1400891

MTMR9
Myotubularin-related protein 9

5

0

High-throughput

0.682

High

665747

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

3

0

High-throughput

0.634

High

1460410

ATIF1
ATPase inhibitor, mitochondrial

1

1

High-throughput

0.618

High

717361

PEBP1
Phosphatidylethanolamine-binding protein 1

3

0

High-throughput

0.606

High

1404107

NELL2
Protein kinase C-binding protein NELL2

2

0

High-throughput

0.602

High

1404085

CYH2
Cytohesin-2

2

1

High-throughput

0.601

High

940634

ATP5E
ATP synthase F(1) complex subunit epsilon, mitochondrial

2

1

High-throughput

0.584

High

1437604

KIF9
Kinesin-like protein KIF9

2

0

High-throughput

0.580

High

1448388

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

1098606

GPS2
G protein pathway suppressor 2

2

0

High-throughput

0.576

High

1438772

GPR35
G-protein coupled receptor 35

2

3

High-throughput

0.574

High

1198148

RHG29
Rho GTPase-activating protein 29

2

2

High-throughput

0.571

High

279966

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.559

High

1391314

CERS2
Ceramide synthase 2

2

1

High-throughput

0.549

High

905780

CAV2
Caveolin-2

2

0

High-throughput

0.547

High

862531

YAP1
Transcriptional coactivator YAP1

1

1

High-throughput

0.536

High

721082

CLIP1
CAP-Gly domain-containing linker protein 1

2

1

High-throughput

0.533

High

1365079

UBXN4
UBX domain-containing protein 4

2

2

High-throughput

0.533

High

1327812

SH2D3
SH2 domain-containing protein 3C

2

1

High-throughput

0.521

High

1088607

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

0

High-throughput

0.518

High

298832

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

1

0

High-throughput

0.513

High

367193

ATP6
ATP synthase F(0) complex subunit a

1

0

High-throughput

0.513

High

397817

ATP8
ATP synthase F(0) complex subunit 8

1

0

High-throughput

0.513

High

530538

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

617619

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

1

0

High-throughput

0.513

High

861829

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

0

High-throughput

0.513

High

870012

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

0

High-throughput

0.513

High

870994

AT5G3
ATP synthase F(0) complex subunit C3, mitochondrial

1

0

High-throughput

0.513

High

940702

ATP5I
ATP synthase F(0) complex subunit e, mitochondrial

1

0

High-throughput

0.513

High

1121992

ARHG7
Rho guanine nucleotide exchange factor 7

1

0

High-throughput

0.513

High

1243788

FXL19
F-box/LRR-repeat protein 19

1

0

High-throughput

0.513

High

1436409

PAAT
ATPase PAAT

1

0

High-throughput

0.513

High

251816

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

1

0

High-throughput

0.493

High

965933

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

0

High-throughput

0.493

High

116883

I6L9F6
NEFL protein

1

0

High-throughput

0.493

High

274797

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.493

High

369771

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.493

High

374998

RASH
GTPase HRas

1

0

High-throughput

0.493

High

442517

GELS
Gelsolin

1

0

High-throughput

0.493

High

650475

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.493

High

702508

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.493

High

896923

DYN2
Dynamin-2

1

0

High-throughput

0.493

High

1199396

GLE1
mRNA export factor GLE1

1

0

High-throughput

0.493

High

141876

ACKR2
Atypical chemokine receptor 2

1

1

High-throughput

0.489

High

833884

P2RY2
P2Y purinoceptor 2

1

2

High-throughput

0.489

High

1142213

P2RY6
P2Y purinoceptor 6

1

2

High-throughput

0.489

High

1439298

E41L5
Band 4.1-like protein 5

1

3

High-throughput

0.489

High

839104

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

0

High-throughput

0.486

High

891866

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.486

High

1448807

UBQL4
Ubiquilin-4

1

0

High-throughput

0.486

High

955731

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.480

High

566871

PDIA4
Protein disulfide-isomerase A4

1

2

High-throughput

0.479

High

616243

PGAM1
Phosphoglycerate mutase 1

1

1

High-throughput

0.479

High

683907

MOES
Moesin

1

3

High-throughput

0.479

High

717635

PDIA3
Protein disulfide-isomerase A3

1

2

High-throughput

0.479

High

767513

RADI
Radixin

1

3

High-throughput

0.479

High

1031588

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.479

High

1046435

UBXN1
UBX domain-containing protein 1

1

1

High-throughput

0.479

High

1135539

RHG19
Rho GTPase-activating protein 19

1

2

High-throughput

0.479

High

1214959

CCD18
Coiled-coil domain-containing protein 18

1

2

High-throughput

0.479

High

1313510

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

1400320

PKH4B
Pleckstrin homology domain-containing family G member 4B

1

1

High-throughput

0.479

High

109531

G5E9A7
DM1 locus, WD repeat containing

1

1

High-throughput

0.470

High

66329

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.458

High

183767

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.458

High

292250

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

0

High-throughput

0.458

High

361372

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.458

High

424470

HMGN1
Non-histone chromosomal protein HMG-14

1

0

High-throughput

0.458

High

459792

PROF1
Profilin-1

1

0

High-throughput

0.458

High

467305

MDR1
ATP-dependent translocase ABCB1

1

0

High-throughput

0.458

High

471312

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

476203

ANXA5
Annexin A5

1

0

High-throughput

0.458

High

481406

HMGB1
High mobility group protein B1

1

0

High-throughput

0.458

High

519264

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

571005

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.458

High

599638

STMN1
Stathmin

1

0

High-throughput

0.458

High

656269

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

0

High-throughput

0.458

High

698064

CALR
Calreticulin

1

0

High-throughput

0.458

High

715834

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

829005

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

842018

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

852072

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

882942

EFTU
Elongation factor Tu, mitochondrial

1

0

High-throughput

0.458

High

885917

KC1E
Casein kinase I isoform epsilon

1

0

High-throughput

0.458

High

992547

RS21
Small ribosomal subunit protein eS21

1

0

High-throughput

0.458

High

992662

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.458

High

1010392

BASP1
Brain acid soluble protein 1

1

0

High-throughput

0.458

High

1040398

DYST
Dystonin

1

0

High-throughput

0.458

High

1058347

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1062858

QOR
Quinone oxidoreductase

1

0

High-throughput

0.458

High

1083794

MPPA
Mitochondrial-processing peptidase subunit alpha

1

0

High-throughput

0.458

High

1090587

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.458

High

1114595

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1207180

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1310742

PHF6
PHD finger protein 6

1

0

High-throughput

0.458

High

1366758

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

0

High-throughput

0.458

High

1381771

FAKD4
FAST kinase domain-containing protein 4

1

0

High-throughput

0.458

High

1388307

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

1394098

RCC1L
RCC1-like G exchanging factor-like protein

1

0

High-throughput

0.458

High

1404920

PARK7
Parkinson disease protein 7

1

0

High-throughput

0.458

High

1412475

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

1414113

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

1418928

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

1419765

ASPC1
Tether containing UBX domain for GLUT4

1

0

High-throughput

0.458

High

1420406

API5
Apoptosis inhibitor 5

1

0

High-throughput

0.458

High

1431996

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

1433752

MTG2
Mitochondrial ribosome-associated GTPase 2

1

0

High-throughput

0.458

High

1435245

ANTR1
Anthrax toxin receptor 1

1

0

Small-scale

0.458

High

1435826

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1436133

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1436746

JUPI2
Jupiter microtubule associated homolog 2

1

0

High-throughput

0.458

High

1449911

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.458

High

1453973

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

1459170

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

0

High-throughput

0.458

High

1459224

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

669083

FPR2
N-formyl peptide receptor 2

1

2

High-throughput

0.445

High

1057025

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.438

High

365489

PGK1
Phosphoglycerate kinase 1

1

1

High-throughput

0.437

High

1092508

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

1

High-throughput

0.437

High

1142426

PDIA6
Protein disulfide-isomerase A6

1

2

High-throughput

0.437

High

1213100

RHG21
Rho GTPase-activating protein 21

1

2

High-throughput

0.437

High

1217697

SYDE2
Rho GTPase-activating protein SYDE2

1

2

High-throughput

0.437

High

1226311

CP135
Centrosomal protein of 135 kDa

1

1

High-throughput

0.437

High

1453593

BFAR
Bifunctional apoptosis regulator

1

1

High-throughput

0.437

High

1212553

CAF17
Iron-sulfur cluster assembly factor IBA57, mitochondrial

1

0

High-throughput

0.426

High

1400464

BTBD9
BTB/POZ domain-containing protein 9

1

0

High-throughput

0.426

High

97265

E9PS44
Interferon induced transmembrane protein 3

1

1

High-throughput

0.407

High

225496

CYH3
Cytohesin-3

1

1

High-throughput

0.407

High

1251759

CERS6
Ceramide synthase 6

1

1

High-throughput

0.407

High

1128860

NBR1
Next to BRCA1 gene 1 protein

2

0

High-throughput

0.313

High

161266

EI24
Etoposide-induced protein 2.4 homolog

1

0

High-throughput

0.279

Low

208417

RRP8
Ribosomal RNA-processing protein 8

1

0

High-throughput

0.279

Low

251126

B4GT3
Beta-1,4-galactosyltransferase 3

1

0

High-throughput

0.279

Low

290787

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.279

Low

625694

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.279

Low

669093

GUC2C
Guanylyl cyclase C

1

0

High-throughput

0.279

Low

689871

CD27
CD27 antigen

1

0

High-throughput

0.279

Low

692278

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

0

High-throughput

0.279

Low

733096

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

0

High-throughput

0.279

Low

902905

BLK
Tyrosine-protein kinase Blk

1

0

High-throughput

0.279

Low

1212773

ZFY27
Protrudin

1

0

High-throughput

0.279

Low

1281398

LHPL4
LHFPL tetraspan subfamily member 4 protein

1

0

High-throughput

0.279

Low

1308014

RELL1
RELT-like protein 1

1

0

High-throughput

0.279

Low

1331634

ZDH22
Palmitoyltransferase ZDHHC22

1

0

High-throughput

0.279

Low

1331800

F133A
Protein FAM133A

1

0

High-throughput

0.279

Low

1332596

THAP8
THAP domain-containing protein 8

1

0

High-throughput

0.279

Low

1394237

TM101
Transmembrane protein 101

1

0

High-throughput

0.279

Low

1397013

SGCZ
Zeta-sarcoglycan

1

0

High-throughput

0.279

Low

1431003

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

1436790

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.279

Low

1446543

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.279

Low

1460411

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.279

Low

1454394

BAHC1
BAH and coiled-coil domain-containing protein 1

1

0

High-throughput

0.269

Low

47430

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

160778

TOR1A
Torsin-1A

1

0

High-throughput

0.268

Low

167416

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.268

Low

458512

ADRB2
Beta-2 adrenergic receptor

1

0

High-throughput

0.268

Low

705598

GRN
Progranulin

1

0

High-throughput

0.268

Low

905262

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.268

Low

1279791

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.268

Low

1415481

NUP58
Nucleoporin p58/p45

1

0

High-throughput

0.268

Low

209351

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

0

High-throughput

0.249

Low

302663

RNF8
E3 ubiquitin-protein ligase RNF8

1

0

Small-scale

0.249

Low

571534

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.249

Low

635809

PTMS
Parathymosin

1

0

High-throughput

0.249

Low

712301

TKT
Transketolase

1

0

High-throughput

0.249

Low

761919

HSP74
Heat shock 70 kDa protein 4

1

0

High-throughput

0.249

Low

872046

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

0

High-throughput

0.249

Low

964499

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.249

Low

971255

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

1219830

ERI6B
Glutamate-rich protein 6B

1

0

High-throughput

0.249

Low

1246202

SPG17
Sperm-associated antigen 17

1

0

High-throughput

0.249

Low

1327252

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

1339753

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.249

Low

1406218

OSMR
Oncostatin-M-specific receptor subunit beta

1

0

Small-scale

0.249

Low

1460412

COR1C
Coronin-1C

1

0

High-throughput

0.249

Low

299852

SNPC5
snRNA-activating protein complex subunit 5

1

0

High-throughput

0.232

Low

1391068

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.232

Low

1413301

WAC
WW domain-containing adapter protein with coiled-coil

1

0

High-throughput

0.232

Low

1420290

S19A3
Thiamine transporter 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025