HitPredict

Interactor 1: E41L2 (O43491)
Band 4.1-like protein 2 (Erythrocyte membrane protein band 4.1-like 2) (Generally expressed protein 4.1) (4.1G)
Gene: EPB41L2

Interactor 2: DIRA3 (O95661)
GTP-binding protein Di-Ras3 (Distinct subgroup of the Ras family member 3) (Rho-related GTP-binding protein RhoI)
Gene: DIRAS3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1005 Hs			1 229
+	Hs
		318222 E41L1_HUMAN (119-1005): 0: 582: 43.06		DIRA3_HUMAN (1-229): 8.18e-88: 260: 100.00
+	Hs
		914356 E41L1_HUMAN (119-1005): 0: 582: 43.06		RB11A_HUMAN (33-227): 1.96e-77: 233: 23.33
+	Hs
		318119 PTN13_HUMAN (79-990): 4.22e-135: 452: 15.70		DIRA3_HUMAN (1-229): 8.18e-88: 260: 100.00
+	Hs
		318229 E41L5_HUMAN (183-830): 3.07e-140: 439: 27.33		DIRA3_HUMAN (1-229): 8.18e-88: 260: 100.00
+	Hs
		914374 E41L5_HUMAN (183-830): 3.07e-140: 439: 27.33		RB11A_HUMAN (33-227): 1.96e-77: 233: 23.33
+	Hs
		318259 FARP1_HUMAN (186-790): 1.21e-124: 407: 27.40		DIRA3_HUMAN (1-229): 8.18e-88: 260: 100.00
+	Hs
		318230 E41LA_HUMAN (215-877): 2.07e-128: 406: 23.98		DIRA3_HUMAN (1-229): 8.18e-88: 260: 100.00
+	Dm
		114271 M9PBW9_DROME (194-1005): 5.11e-117: 399: 13.53		O96692_DROME (35-196): 1.73e-22: 92: 35.58
+	Hs
		505614 EPB41_HUMAN (649-1002): 1.05e-46: 182: 32.78		RB11A_HUMAN (33-227): 1.96e-77: 233: 23.33
+	Hs
		505602 EPB41_HUMAN (649-1002): 1.05e-46: 182: 32.78		RAB10_HUMAN (29-227): 1.76e-75: 228: 19.21
+	Hs
		505642 EPB41_HUMAN (649-1002): 1.05e-46: 182: 32.78		RB11B_HUMAN (33-227): 1.78e-75: 228: 22.64