Interactor 1: AXIN1 (O35625)
Axin-1 (Axis inhibition protein 1) (Protein Fused)
Gene: AXIN1
Interactor 2: PIAS1 (O88907)
E3 SUMO-protein ligase PIAS1 (EC 2.3.2.27) (DEAD/H box-binding protein 1) (Protein inhibitor of activated STAT protein 1) (RING-type E3 ubiquitin transferase PIAS1)
Gene: PIAS1
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.50 | 0.60 | 0.552 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12223491 |
| Identification Methods | two hybrid, affinity chromatography technology |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0019904 - protein domain specific binding GO:0031625 - ubiquitin protein ligase binding GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
