Protein: AXIN1
Axin-1 (Axis inhibition protein 1) (Protein Fused)

Gene: AXIN1
Organism: Mus musculus
Interactions: 39
UniProt ID: O35625

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0001701 - in utero embryonic development
GO:0002039 - p53 binding
GO:0005634 - nucleus
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

205258

CTNB1
Catenin beta-1

8

7

Small-scale

0.958

High

205276

GSK3B
Glycogen synthase kinase-3 beta

7

7

Small-scale

0.957

High

205243

AXIN1
Axin-1

4

7

Small-scale

0.904

High

148036

M3K4
Mitogen-activated protein kinase kinase kinase 4

2

8

Small-scale

0.806

High

205265

Q8BNP7
Adenomatous polyposis coli protein

2

8

Small-scale

0.768

High

205251

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

2

1

Small-scale

0.754

High

107131

F8VQ72
Mitogen-activated protein kinase kinase kinase 1

1

4

Small-scale

0.724

High

205259

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

Small-scale

0.691

High

205270

LRP5
Low-density lipoprotein receptor-related protein 5

3

5

Small-scale

0.661

High

205261

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

16

Small-scale

0.646

High

205256

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

2

5

Small-scale

0.631

High

205260

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

14

Small-scale

0.618

High

205264

DIXC1
Dixin

1

8

Small-scale

0.618

High

205275

HIPK2
Homeodomain-interacting protein kinase 2

1

3

Small-scale

0.618

High

205257

DAB2
Disabled homolog 2

2

2

Small-scale

0.601

High

205271

RN111
E3 ubiquitin-protein ligase Arkadia

1

3

Small-scale

0.586

High

205247

P53
Cellular tumor antigen p53

2

1

Small-scale

0.584

High

205250

KIF3A
Kinesin-like protein KIF3A

1

6

Small-scale

0.561

High

205273

ANM1
Protein arginine N-methyltransferase 1

1

4

Small-scale

0.561

High

205246

PIAS1
E3 SUMO-protein ligase PIAS1

1

2

Small-scale

0.552

High

205268

PIAS2
E3 SUMO-protein ligase PIAS2

1

2

Small-scale

0.552

High

205245

LRP6
Low-density lipoprotein receptor-related protein 6

2

5

Small-scale

0.552

High

205272

WWTR1
WW domain-containing transcription regulator protein 1

1

5

Small-scale

0.536

High

204416

SMAD6
Mothers against decapentaplegic homolog 6

1

7

Small-scale

0.515

High

204535

SMAD7
Mothers against decapentaplegic homolog 7

1

7

Small-scale

0.515

High

205266

SMAD3
Mothers against decapentaplegic homolog 3

1

7

Small-scale

0.515

High

205244

NCK2
Cytoplasmic protein NCK2

1

3

Small-scale

0.481

High

205274

PIAS4
E3 SUMO-protein ligase PIAS4

1

2

Small-scale

0.481

High

205249

CADH2
Cadherin-2

1

1

Small-scale

0.479

High

205252

HD
Huntingtin

1

3

Small-scale

0.479

High

205254

CSN2
COP9 signalosome complex subunit 2

1

1

Small-scale

0.479

High

205255

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

4

Small-scale

0.479

High

205263

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

2

Small-scale

0.479

High

205267

AIDA
Axin interactor, dorsalization-associated protein

1

0

Small-scale

0.458

High

205269

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.458

High

205253

YAP1
Transcriptional coactivator YAP1

1

5

Small-scale

0.445

High

205262

XPO1
Exportin-1

1

3

Small-scale

0.445

High

205248

CFAD
Complement factor D

1

1

High-throughput

0.437

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025