HitPredict

Interactor 1: RA51C (O43502)
DNA repair protein RAD51 homolog 3 (R51H3) (RAD51 homolog C) (RAD51-like protein 2)
Gene: RAD51C

Interactor 2: XRCC2 (O43543)
DNA repair protein XRCC2 (X-ray repair cross-complementing protein 2)
Gene: XRCC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 24141787, 11842112, 11744692, 11842113, 26186194, 28514442, 11751635, 33961781
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Rad51~Rad51
Common GO terms GO:0000400 - four-way junction DNA binding
GO:0000724 - double-strand break repair via homologous recombination
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005657 - replication fork
and 5 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 376
Hs

1 280
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+ At
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+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024