Interactor 1: WIPF1 (O43516)
WAS/WASL-interacting protein family member 1 (Protein PRPL-2) (Wiskott-Aldrich syndrome protein-interacting protein) (WASP-interacting protein)
Gene: WIPF1

Interactor 2: WASP (P42768)
Actin nucleation-promoting factor WAS (Wiskott-Aldrich syndrome protein) (WASp)
Gene: WAS

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 9694849, 25416956, 32296183, 9405671, 21988832, 17213309, 19805221, unassigned1304, 19817875, 12591280, 10202051, 16488394
Identification Methods two hybrid, affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid, gal4 vp16 complementation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains WH2~WH2
Common GO terms GO:0003779 - actin binding
GO:0005829 - cytosol
GO:0005884 - actin filament
GO:0008154 - actin polymerization or depolymerization
GO:0015629 - actin cytoskeleton
and 3 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 503
Hs

1 502
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024