HitPredict

Interactor 1: B2L11 (O43521)
Bcl-2-like protein 11 (Bcl2-L-11) (Bcl2-interacting mediator of cell death)
Gene: BCL2L11

Interactor 2: B2CL1 (Q07817)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: BCL2L1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.990

The method score is based on:

Property Details
Experiments 19427863, 27013495, 20836993, 15694340, 32296183, 9430630, 33961781, 9731710, 15721256, 16697956, 26186194, 28514442, 14596824, 34667112, 16260615, unassigned1304, 21199865, 17289999, 23245996, 21671007 and 2 others

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Identification Methods affinity chromatography technology, two hybrid, unspecified method, fluorescent resonance energy transfer, fluorescence polarization spectroscopy, validated two hybrid, mammalian protein protein interaction trap, surface plasmon resonance, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation and 4 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~Bclx_interact
Common GO terms GO:0001701 - in utero embryonic development
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol
GO:0007283 - spermatogenesis
and 5 others

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Homologous interactions 17

Homologous interactions

Color coding for hit scores

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Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024