Interactor 1: LAT (O43561)
Linker for activation of T-cells family member 1 (36 kDa phosphotyrosine adapter protein) (pp36) (p36-38)
Gene: LAT
Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.94 | 0.60 | 0.752 |
The method score is based on:
Property | Details |
---|---|
Experiments | 11368773, 9489702, 12186560, 7544353, 8063801, 16906159, 16938345, 23460737, 10811803 |
Identification Methods | affinity chromatography technology, pull down, isothermal titration calorimetry, cosedimentation in solution, anti bait coimmunoprecipitation, coimmunoprecipitation |
Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | - |
Common GO terms | GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0007265 - Ras protein signal transduction GO:0008180 - COP9 signalosome and 1 others more... |
Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024