Interactor 1: LAT (O43561)
Linker for activation of T-cells family member 1 (36 kDa phosphotyrosine adapter protein) (pp36) (p36-38)
Gene: LAT

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.752

The method score is based on:

Property Details
Experiments 11368773, 9489702, 12186560, 7544353, 8063801, 16906159, 16938345, 23460737, 10811803
Identification Methods affinity chromatography technology, pull down, isothermal titration calorimetry, cosedimentation in solution, anti bait coimmunoprecipitation, coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0007265 - Ras protein signal transduction
GO:0008180 - COP9 signalosome
and 1 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 262
Hs

1 217
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024