Interactor 1: LAT (O43561)
Linker for activation of T-cells family member 1 (36 kDa phosphotyrosine adapter protein) (pp36) (p36-38)
Gene: LAT

Interactor 2: LCP2 (Q13094)
Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76)
Gene: LCP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.571

The method score is based on:

Property Details
Experiments 23514740, 24584089
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005911 - cell-cell junction
GO:0006955 - immune response
GO:0035556 - intracellular signal transduction
GO:0036398 - TCR signalosome
GO:0045860 - positive regulation of protein kinase activity
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 262
Hs

1 533
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024