Interactor 1: RGS14 (O43566)
Regulator of G-protein signaling 14 (RGS14)
Gene: RGS14
Interactor 2: GNAI3 (P08754)
Guanine nucleotide-binding protein G(i) subunit alpha-3 (G(i) alpha-3)
Gene: GNAI3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.965 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11387333, 26186194, 28514442, 32296183, 33961781, 21988832, unassigned1304 |
| Identification Methods | two hybrid, affinity chromatography technology, pull down, validated two hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | G-alpha~GoLoco, G-alpha~RGS |
| Common GO terms | GO:0003924 - GTPase activity GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005886 - plasma membrane GO:0051301 - cell division |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
