HitPredict

Interactor 1: SPY2 (O43597)
Protein sprouty homolog 2 (Spry-2)
Gene: SPRY2

Interactor 2: KR101 (P60331)
Keratin-associated protein 10-1 (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1)
Gene: KRTAP10-1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	25416956
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 315 Hs			1 282
+	Hs
		208123 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KR10B_HUMAN (1-282): 1.51e-66: 211: 84.32
+	Hs
		208120 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KR105_HUMAN (1-282): 9.07e-61: 195: 88.30
+	Hs
		208347 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KR10B_HUMAN (1-282): 1.51e-66: 211: 84.32
+	Hs
		208341 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KR101_HUMAN (1-282): 1.42e-65: 208: 100.00
+	Hs
		208343 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KR105_HUMAN (1-282): 9.07e-61: 195: 88.30
+	Hs
		208122 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KR109_HUMAN (3-204): 2.86e-29: 114: 39.19
+	Hs
		208191 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KRA47_HUMAN (133-282): 1.23e-18: 82.5: 34.84
+	Hs
		208344 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KR107_HUMAN (2-239): 3.7e-38: 139: 46.83
+	Hs
		208183 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KR412_HUMAN (2-194): 2.15e-14: 72.1: 31.61
+	Hs
		208188 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KRA94_HUMAN (54-203): 3.6e-14: 70.2: 29.68
+	Hs
		208119 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KR103_HUMAN (149-282): 6.84e-13: 68.3: 35.15
+	Hs
		208189 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KRA92_HUMAN (14-169): 4.94e-13: 67.5: 24.36
+	Hs
		208121 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KR108_HUMAN (1-146): 2.65e-11: 64.4: 24.66
+	Hs
		208190 SPY2_HUMAN (1-315): 1.24e-136: 391: 100.00		KR411_HUMAN (180-282): 2.05e-09: 57.9: 38.10
+	Hs
		208346 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KR109_HUMAN (3-204): 2.86e-29: 114: 39.19
+	Hs
		208342 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KR103_HUMAN (149-282): 6.84e-13: 68.3: 35.15
+	Hs
		208339 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KR122_HUMAN (151-282): 1.25e-12: 65.9: 32.35
+	Hs
		208345 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KR108_HUMAN (1-146): 2.65e-11: 64.4: 24.66
+	Hs
		208352 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KRA11_HUMAN (30-209): 4.29e-10: 59.4: 27.07
+	Hs
		208340 SPY1_HUMAN (1-315): 1.06e-110: 325: 51.67		KR123_HUMAN (67-163): 3.76e-09: 54.9: 30.93