HitPredict

Interactor 1: CHM2A (O43633)
Charged multivesicular body protein 2a (Chromatin-modifying protein 2a) (CHMP2a) (Putative breast adenocarcinoma marker BC-2) (Vacuolar protein sorting-associated protein 2-1) (Vps2-1) (hVps2-1)
Gene: CHMP2A

Interactor 2: CHMP5 (Q9NZZ3)
Charged multivesicular body protein 5 (Chromatin-modifying protein 5) (SNF7 domain-containing protein 2) (Vacuolar protein sorting-associated protein 60) (Vps60) (hVps60)
Gene: CHMP5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Snf7~Snf7
Common GO terms GO:0000421 - autophagosome membrane
GO:0000776 - kinetochore
GO:0001778 - plasma membrane repair
GO:0005643 - nuclear pore
GO:0005765 - lysosomal membrane
and 27 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 222
Hs

1 219
+ At
+ Ce
+ At
+ At
+ Hs
+ Hs
+ Sc
+ Sc
+ Dm
+ Sc
+ At
+ Hs
+ Sc
+ At
+ At
+ At
+ At
+ Dm
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024