HitPredict

Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: SF01 (Q15637)
Splicing factor 1 (Mammalian branch point-binding protein) (BBP) (mBBP) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Zinc finger protein 162)
Gene: SF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.50	0.553

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 380 Hs			1 639
+	Hs
		209037 NCK2_HUMAN (1-380): 6.88e-99: 300: 100.00		KHDR1_HUMAN (135-252): 2.61e-25: 111: 29.92
+	Mm
		1141333 NCK1_MOUSE (1-379): 6.79e-91: 279: 68.24		KHDR1_MOUSE (81-435): 1.48e-30: 126: 17.58
+	Hs
		557667 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		KHDR1_HUMAN (135-252): 2.61e-25: 111: 29.92
+	Mm
		763412 FYN_MOUSE (7-137): 2.1e-23: 103: 20.30		KHDR2_MOUSE (82-431): 1.42e-42: 159: 19.72
+	Mm
		1141173 GRB2_MOUSE (1-61): 1.04e-18: 85.9: 27.42		KHDR2_MOUSE (82-431): 1.42e-42: 159: 19.72
+	Hs
		782780 CSK_HUMAN (191-378): 3.44e-32: 127: 24.87		KHDR1_HUMAN (135-252): 2.61e-25: 111: 29.92
+	Rn
		1144374 P85A_RAT (163-379): 8.5e-24: 105: 16.14		KHDR1_RAT (81-435): 6.66e-30: 124: 17.58
+	Mm
		763394 FYN_MOUSE (7-137): 2.1e-23: 103: 20.30		KHDR1_MOUSE (81-435): 1.48e-30: 126: 17.58
+	Hs
		991902 ITSN2_HUMAN (3-309): 6.32e-28: 117: 18.31		KHDR1_HUMAN (135-252): 2.61e-25: 111: 29.92
+	Mm
		403437 SRC_MOUSE (6-153): 5.44e-20: 93.3: 17.33		KHDR1_MOUSE (81-435): 1.48e-30: 126: 17.58
+	Hs
		655330 P85A_HUMAN (166-379): 4.05e-24: 106: 16.36		KHDR1_HUMAN (135-252): 2.61e-25: 111: 29.92
+	Hs
		454827 FGR_HUMAN (7-155): 1.02e-23: 104: 18.54		KHDR1_HUMAN (135-252): 2.61e-25: 111: 29.92
+	Hs
		412149 FYN_HUMAN (7-137): 2.1e-23: 103: 20.30		KHDR1_HUMAN (135-252): 2.61e-25: 111: 29.92
+	Hs
		442815 HCK_HUMAN (2-145): 5.1e-23: 102: 24.83		KHDR1_HUMAN (135-252): 2.61e-25: 111: 29.92
+	Mm
		1141126 GRB2_MOUSE (1-61): 1.04e-18: 85.9: 27.42		KHDR1_MOUSE (81-435): 1.48e-30: 126: 17.58
+	Hs
		991778 ITSN1_HUMAN (6-70): 3.77e-19: 91.7: 29.23		KHDR1_HUMAN (135-252): 2.61e-25: 111: 29.92
+	Hs
		411689 LCK_HUMAN (3-145): 6.3e-19: 90.2: 21.53		KHDR1_HUMAN (135-252): 2.61e-25: 111: 29.92
+	Hs
		789110 FRK_HUMAN (3-132): 2.88e-18: 88.3: 18.71		KHDR1_HUMAN (135-252): 2.61e-25: 111: 29.92
+	Hs
		924509 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		KHDR1_HUMAN (135-252): 2.61e-25: 111: 29.92
+	Hs
		991842 SH3K1_HUMAN (8-109): 4.25e-16: 82: 16.35		KHDR1_HUMAN (135-252): 2.61e-25: 111: 29.92