HitPredict

Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: NHSL2 (Q5HYW2)
NHS-like protein 2
Gene: NHSL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.50	0.537

Property	Details
Experiments	28514442, unassigned1304
Identification Methods	anti tag coimmunoprecipitation, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 1225
+	Hs
		557708 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		NHSL2_HUMAN (1-1225): 1.51e-132: 438: 100.00
+	Hs
		209086 NCK2_HUMAN (1-380): 6.88e-99: 300: 100.00		NHS_HUMAN (22-537): 7.53e-24: 111: 18.67
+	Hs
		209076 NCK2_HUMAN (1-380): 6.88e-99: 300: 100.00		NHSL1_HUMAN (91-1218): 1.41e-13: 77.8: 12.38
+	Hs
		203208 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		SYNJ1_HUMAN (681-1221): 8.18e-14: 78.6: 11.01
+	Hs
		557712 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		NHSL1_HUMAN (91-1218): 1.41e-13: 77.8: 12.38
+	Hs
		64077 SRC_HUMAN (203-361): 5.72e-16: 81.3: 31.55		L37A2_HUMAN (332-1162): 6.91e-72: 266: 13.90
+	Hs
		411582 LCK_HUMAN (3-145): 6.3e-19: 90.2: 21.53		MUC1_HUMAN (60-763): 7.2e-32: 137: 9.54
+	Hs
		924760 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		PRG4_HUMAN (582-1225): 4.14e-32: 138: 9.74
+	Hs
		554292 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		MUC1_HUMAN (60-763): 7.2e-32: 137: 9.54
+	Hs
		522749 SRC_HUMAN (203-361): 5.72e-16: 81.3: 31.55		MUC1_HUMAN (60-763): 7.2e-32: 137: 9.54
+	Hs
		1349277 ITSN2_HUMAN (3-309): 6.32e-28: 117: 18.31		DAPLE_HUMAN (669-1225): 2.83e-10: 67.4: 15.66
+	Hs
		203228 ITSN1_HUMAN (6-70): 3.77e-19: 91.7: 29.23		SYNJ1_HUMAN (681-1221): 8.18e-14: 78.6: 11.01
+	Hs
		203198 LCK_HUMAN (3-145): 6.3e-19: 90.2: 21.53		SYNJ1_HUMAN (681-1221): 8.18e-14: 78.6: 11.01
+	Hs
		412362 FYN_HUMAN (7-137): 2.1e-23: 103: 20.30		MAGE1_HUMAN (763-1187): 6.27e-09: 62.7: 11.77
+	Hs
		203218 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		SYNJ1_HUMAN (681-1221): 8.18e-14: 78.6: 11.01
+	Hs
		1056926 SH3K1_HUMAN (8-109): 4.25e-16: 82: 16.35		MDC1_HUMAN (76-865): 1.61e-14: 81.2: 8.82
+	Hs
		203230 SH319_HUMAN (1-57): 2.18e-16: 82.8: 19.30		SYNJ1_HUMAN (681-1221): 8.18e-14: 78.6: 11.01
+	Hs
		203241 SH3K1_HUMAN (8-109): 4.25e-16: 82: 16.35		SYNJ1_HUMAN (681-1221): 8.18e-14: 78.6: 11.01