Protein: KLH20
Kelch-like protein 20 (Kelch-like ECT2-interacting protein) (Kelch-like protein X)

Gene: KLH20, KLHL20
Organism: Homo sapiens
Interactions: 219
UniProt ID: Q9Y2M5

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005802 - trans-Golgi network

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1042881

CUL3
Cullin-3

11

20

Small-scale

0.979

High

1354642

FXL17
F-box/LRR-repeat protein 17

4

15

High-throughput

0.892

High

1377325

IPP
Actin-binding protein IPP

3

19

High-throughput

0.861

High

1121285

KLH22
Kelch-like protein 22

2

19

High-throughput

0.811

High

1377330

NS1BP
Influenza virus NS1A-binding protein

1

19

Small-scale

0.770

High

1121511

KLH26
Kelch-like protein 26

3

20

High-throughput

0.770

High

669089

PML
Protein PML

4

5

Small-scale

0.715

High

884662

CORO7
Coronin-7

4

5

Small-scale

0.705

High

862134

DAPK1
Death-associated protein kinase 1

3

1

Small-scale

0.698

High

213874

SYNC
Asparagine--tRNA ligase, cytoplasmic

3

1

High-throughput

0.667

High

901066

RHOA
Transforming protein RhoA

3

1

High-throughput

0.667

High

1190744

HDGR2
Hepatoma-derived growth factor-related protein 2

3

1

High-throughput

0.667

High

1217464

NUDC3
NudC domain-containing protein 3

3

20

High-throughput

0.667

High

1316170

PDIP3
Polymerase delta-interacting protein 3

3

1

High-throughput

0.667

High

1347915

MIOS
GATOR2 complex protein MIOS

3

2

High-throughput

0.667

High

1357688

TRI33
E3 ubiquitin-protein ligase TRIM33

3

6

High-throughput

0.667

High

1377320

KLH20
Kelch-like protein 20

1

19

Small-scale

0.647

High

134712

PIR
Pirin

3

0

High-throughput

0.638

High

878625

ALR
FAD-linked sulfhydryl oxidase ALR

3

0

High-throughput

0.638

High

1103460

CTU2
Cytoplasmic tRNA 2-thiolation protein 2

3

0

High-throughput

0.638

High

199563

M3K13
Mitogen-activated protein kinase kinase kinase 13

2

2

High-throughput

0.628

High

964539

RELB
Transcription factor RelB

2

1

High-throughput

0.628

High

781493

BCL6
B-cell lymphoma 6 protein

1

2

High-throughput

0.621

High

64225

UBP27
Ubiquitin carboxyl-terminal hydrolase 27

2

3

High-throughput

0.611

High

282290

CDKL5
Cyclin-dependent kinase-like 5

2

2

High-throughput

0.611

High

603266

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

2

3

High-throughput

0.611

High

674991

PUR8
Adenylosuccinate lyase

2

1

High-throughput

0.611

High

1302657

MA7D2
MAP7 domain-containing protein 2

3

2

High-throughput

0.609

High

1345828

RBM12
RNA-binding protein 12

3

1

High-throughput

0.609

High

701750

CGL
Cystathionine gamma-lyase

2

0

High-throughput

0.602

High

252770

FCG3B
Low affinity immunoglobulin gamma Fc region receptor III-B

3

4

High-throughput

0.599

High

848165

MECP2
Methyl-CpG-binding protein 2

2

0

High-throughput

0.594

High

1333823

ECT2
Protein ECT2

2

5

Small-scale

0.586

High

1269082

NEUG
Neurogranin

2

0

High-throughput

0.585

High

1120830

KLH12
Kelch-like protein 12

1

20

High-throughput

0.575

High

1164636

KLH24
Kelch-like protein 24

1

20

High-throughput

0.575

High

1356007

KLH21
Kelch-like protein 21

1

18

High-throughput

0.575

High

1377328

PCDG5
Protocadherin gamma-A5

2

3

High-throughput

0.574

High

613024

TCEA1
Transcription elongation factor A protein 1

2

1

High-throughput

0.558

High

1103553

KLH38
Kelch-like protein 38

1

20

High-throughput

0.555

High

1241845

ZBT44
Zinc finger and BTB domain-containing protein 44

1

20

High-throughput

0.553

High

1306556

EPAS1
Endothelial PAS domain-containing protein 1

1

3

Small-scale

0.552

High

789193

HELZ
Probable helicase with zinc finger domain

2

1

High-throughput

0.552

High

1050909

DPYL1
Dihydropyrimidinase-related protein 1

1

1

High-throughput

0.541

High

433003

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

1

High-throughput

0.536

High

443891

VIME
Vimentin

1

2

High-throughput

0.536

High

453717

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

1

High-throughput

0.536

High

509169

TOP2A
DNA topoisomerase 2-alpha

1

2

High-throughput

0.536

High

631638

BRD2
Bromodomain-containing protein 2

1

4

High-throughput

0.536

High

833543

RBM25
RNA-binding protein 25

1

4

High-throughput

0.536

High

896269

UBC12
NEDD8-conjugating enzyme Ubc12

1

14

High-throughput

0.536

High

973418

TOP2B
DNA topoisomerase 2-beta

1

2

High-throughput

0.536

High

992154

B2CL1
Bcl-2-like protein 1

1

1

High-throughput

0.536

High

1049543

SAFB2
Scaffold attachment factor B2

1

5

High-throughput

0.536

High

1057433

SMC1A
Structural maintenance of chromosomes protein 1A

1

3

High-throughput

0.536

High

1202487

HOOK3
Protein Hook homolog 3

1

6

High-throughput

0.536

High

1232593

STAG2
Cohesin subunit SA-2

1

1

High-throughput

0.536

High

1233568

MINK1
Misshapen-like kinase 1

1

3

High-throughput

0.536

High

1256140

UTP15
U3 small nucleolar RNA-associated protein 15 homolog

1

3

High-throughput

0.536

High

1256953

DOK4
Docking protein 4

1

2

High-throughput

0.536

High

1261593

STAG1
Cohesin subunit SA-1

1

1

High-throughput

0.536

High

1265994

AP2B
Transcription factor AP-2-beta

1

2

High-throughput

0.536

High

1302249

STRBP
Spermatid perinuclear RNA-binding protein

1

2

High-throughput

0.536

High

1313921

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

1

High-throughput

0.536

High

1342659

UBE2T
Ubiquitin-conjugating enzyme E2 T

1

6

High-throughput

0.536

High

1345703

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

1

2

High-throughput

0.536

High

1349178

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

2

High-throughput

0.536

High

1357810

COR2B
Coronin-2B

1

4

High-throughput

0.536

High

1297040

ANM6
Protein arginine N-methyltransferase 6

1

2

High-throughput

0.523

High

690158

GBP2
Guanylate-binding protein 2

1

0

High-throughput

0.518

High

1038091

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

High-throughput

0.518

High

1350347

CE126
Centrosomal protein of 126 kDa

1

0

High-throughput

0.518

High

1185018

CSN6
COP9 signalosome complex subunit 6

1

8

High-throughput

0.515

High

158061

KLF11
Krueppel-like factor 11

1

2

High-throughput

0.515

High

158251

GIPC1
PDZ domain-containing protein GIPC1

1

2

High-throughput

0.515

High

229108

PRKN
E3 ubiquitin-protein ligase parkin

1

17

High-throughput

0.515

High

231769

KIF1B
Kinesin-like protein KIF1B

1

2

High-throughput

0.515

High

281957

WFS1
Wolframin

1

1

High-throughput

0.515

High

358936

CRYAA
Alpha-crystallin A chain

1

2

High-throughput

0.515

High

388813

HSPB1
Heat shock protein beta-1

1

2

High-throughput

0.515

High

414119

GELS
Gelsolin

1

1

High-throughput

0.515

High

535609

GFAP
Glial fibrillary acidic protein

1

2

High-throughput

0.515

High

609618

FGFR3
Fibroblast growth factor receptor 3

1

2

High-throughput

0.515

High

660767

GRN
Progranulin

1

1

High-throughput

0.515

High

667736

NOS3
Nitric oxide synthase 3

1

1

High-throughput

0.515

High

792109

HD
Huntingtin

1

1

High-throughput

0.515

High

803816

BAG6
Large proline-rich protein BAG6

1

2

High-throughput

0.515

High

868814

ATX1
Ataxin-1

1

4

High-throughput

0.515

High

893510

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

1

High-throughput

0.515

High

1026251

PAK1
Serine/threonine-protein kinase PAK 1

1

7

High-throughput

0.515

High

1051524

DCTN1
Dynactin subunit 1

1

4

High-throughput

0.515

High

1121147

GLE1
mRNA export factor GLE1

1

4

High-throughput

0.515

High

1191636

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.515

High

224556

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.513

High

252938

MITF
Microphthalmia-associated transcription factor

1

0

High-throughput

0.513

High

451612

CLCA
Clathrin light chain A

1

0

High-throughput

0.513

High

948857

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

0

High-throughput

0.513

High

964083

SRSF2
Serine/arginine-rich splicing factor 2

1

0

High-throughput

0.513

High

970614

ID2
DNA-binding protein inhibitor ID-2

1

0

High-throughput

0.513

High

1058847

LBR
Delta(14)-sterol reductase LBR

1

0

High-throughput

0.513

High

1062715

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.513

High

1244762

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.513

High

1307532

VRK1
Serine/threonine-protein kinase VRK1

1

0

High-throughput

0.513

High

1310375

PYM1
Partner of Y14 and mago

1

0

High-throughput

0.513

High

1377323

NOC2L
Nucleolar complex protein 2 homolog

1

0

High-throughput

0.513

High

933075

ACTS
Actin, alpha skeletal muscle

1

7

Small-scale

0.501

High

1349335

ARHGC
Rho guanine nucleotide exchange factor 12

1

3

Small-scale

0.501

High

156687

PAHX
Phytanoyl-CoA dioxygenase, peroxisomal

1

0

High-throughput

0.493

High

204087

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.493

High

448139

DOPO
Dopamine beta-hydroxylase

1

0

High-throughput

0.493

High

742622

SYUA
Alpha-synuclein

1

0

High-throughput

0.493

High

868375

ATX3
Ataxin-3

1

0

High-throughput

0.493

High

1271984

KLK6
Kallikrein-6

1

0

High-throughput

0.493

High

229527

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

2

High-throughput

0.489

High

245114

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.489

High

261046

H2AY
Core histone macro-H2A.1

1

3

High-throughput

0.489

High

658752

SMCA1
Probable global transcription activator SNF2L1

1

2

High-throughput

0.489

High

800558

CBX5
Chromobox protein homolog 5

1

3

High-throughput

0.489

High

996969

SSRP1
FACT complex subunit SSRP1

1

6

High-throughput

0.489

High

1016349

TBL3
Transducin beta-like protein 3

1

5

High-throughput

0.489

High

1057032

MDC1
Mediator of DNA damage checkpoint protein 1

1

3

High-throughput

0.489

High

1067261

WDR43
WD repeat-containing protein 43

1

3

High-throughput

0.489

High

1070057

PWP2
Periodic tryptophan protein 2 homolog

1

4

High-throughput

0.489

High

1073573

SAFB1
Scaffold attachment factor B1

1

4

High-throughput

0.489

High

1087141

H2A2C
Histone H2A type 2-C

1

1

High-throughput

0.489

High

1161627

SYDM
Aspartate--tRNA ligase, mitochondrial

1

1

High-throughput

0.489

High

1216284

H2A2B
Histone H2A type 2-B

1

1

High-throughput

0.489

High

1246505

WDR36
WD repeat-containing protein 36

1

3

High-throughput

0.489

High

1282734

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

3

High-throughput

0.489

High

1289272

RMXL1
RNA binding motif protein, X-linked-like-1

1

2

High-throughput

0.489

High

1290573

TMA16
Translation machinery-associated protein 16

1

1

High-throughput

0.489

High

1302722

RBM15
RNA-binding protein 15

1

1

High-throughput

0.489

High

1348128

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

1

High-throughput

0.489

High

1349699

H2AW
Core histone macro-H2A.2

1

3

High-throughput

0.489

High

1355781

BAZ1B
Tyrosine-protein kinase BAZ1B

1

5

High-throughput

0.489

High

1356526

RALY
RNA-binding protein Raly

1

1

High-throughput

0.489

High

1357604

WDR3
WD repeat-containing protein 3

1

5

High-throughput

0.489

High

1377327

PCDG6
Protocadherin gamma-A6

1

3

High-throughput

0.489

High

1377329

UTP18
U3 small nucleolar RNA-associated protein 18 homolog

1

2

High-throughput

0.489

High

155665

TNPO2
Transportin-2

1

3

High-throughput

0.481

High

274308

STK16
Serine/threonine-protein kinase 16

1

5

High-throughput

0.481

High

802786

CRK
Adapter molecule crk

1

3

High-throughput

0.481

High

1054801

CASL
Enhancer of filamentation 1

1

3

High-throughput

0.481

High

1188455

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.481

High

1205971

S13A5
Na(+)/citrate cotransporter

1

1

High-throughput

0.481

High

1284500

CIDEC
Lipid transferase CIDEC

1

1

High-throughput

0.481

High

1293328

NTAQ1
Protein N-terminal glutamine amidohydrolase

1

4

High-throughput

0.481

High

1315987

BEX2
Protein BEX2

1

3

High-throughput

0.481

High

1331944

DUS21
Dual specificity protein phosphatase 21

1

2

High-throughput

0.481

High

1332604

RANB3
Ran-binding protein 3

1

3

High-throughput

0.481

High

1335454

BEX1
Protein BEX1

1

3

High-throughput

0.481

High

1377298

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

8

High-throughput

0.481

High

163497

XPO1
Exportin-1

1

6

High-throughput

0.479

High

1036507

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

1

High-throughput

0.479

High

1047851

CKAP5
Cytoskeleton-associated protein 5

1

1

High-throughput

0.479

High

1134166

UBAP2
Ubiquitin-associated protein 2

1

3

High-throughput

0.479

High

1218200

CEP97
Centrosomal protein of 97 kDa

1

4

Small-scale

0.479

High

1262741

ATX2L
Ataxin-2-like protein

1

2

High-throughput

0.479

High

1267575

TSC1
Hamartin

1

6

High-throughput

0.479

High

1315193

OSB11
Oxysterol-binding protein-related protein 11

1

2

High-throughput

0.479

High

1347430

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

1

High-throughput

0.479

High

103871

G5E9A7
DM1 locus, WD repeat containing

1

1

High-throughput

0.470

High

1026020

TADBP
TAR DNA-binding protein 43

1

5

High-throughput

0.470

High

1203648

Q86WV8
TSC complex subunit 1

1

1

High-throughput

0.470

High

1377322

RNF11
RING finger protein 11

1

1

High-throughput

0.470

High

815943

MTR1A
Melatonin receptor type 1A

1

3

High-throughput

0.464

High

588970

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.458

High

1189976

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.458

High

1201353

SERC5
Serine incorporator 5

1

0

Small-scale

0.458

High

1334121

CNO10
CCR4-NOT transcription complex subunit 10

1

0

High-throughput

0.458

High

1137599

RIF1
Telomere-associated protein RIF1

1

5

High-throughput

0.457

High

1292409

DCNL1
DCN1-like protein 1

1

9

High-throughput

0.445

High

208066

HAIR
Lysine-specific demethylase hairless

1

1

High-throughput

0.439

High

328466

RECK
Reversion-inducing cysteine-rich protein with Kazal motifs

1

3

High-throughput

0.439

High

650168

CO8A1
Collagen alpha-1(VIII) chain

1

6

High-throughput

0.439

High

850455

CLCKA
Chloride channel protein ClC-Ka

1

1

High-throughput

0.439

High

885756

CU058
Uncharacterized protein C21orf58

1

1

High-throughput

0.439

High

1192081

AP2D
Transcription factor AP-2-delta

1

2

High-throughput

0.439

High

1250888

CA216
UPF0500 protein C1orf216

1

1

High-throughput

0.439

High

1327856

ENKD1
Enkurin domain-containing protein 1

1

2

High-throughput

0.439

High

1328799

CMIP1
Ciliary microtubule inner protein 1

1

2

High-throughput

0.439

High

1297624

CCDC7
Coiled-coil domain-containing protein 7

1

4

High-throughput

0.437

High

92676

E9PNY5
Low affinity immunoglobulin gamma Fc region receptor III-A

1

1

High-throughput

0.407

High

61147

KRBA1
Protein KRBA1

3

0

High-throughput

0.347

High

263071

SPAG7
Sperm-associated antigen 7

3

0

High-throughput

0.347

High

830198

PRI2
DNA primase large subunit

3

0

High-throughput

0.347

High

1357777

SATB2
DNA-binding protein SATB2

3

0

High-throughput

0.347

High

1343469

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

2

0

High-throughput

0.328

High

830160

PRI1
DNA primase small subunit

2

0

High-throughput

0.318

High

1079806

EREP1
Endosomal transmembrane epsin interactor 1

2

0

High-throughput

0.318

High

1159618

PDXD2
Putative pyridoxal-dependent decarboxylase domain-containing protein 2

2

0

High-throughput

0.288

High

1356553

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.282

High

1377321

LC7L2
Putative RNA-binding protein Luc7-like 2

1

0

High-throughput

0.282

High

256599

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

0

High-throughput

0.279

Low

567790

UBF1
Nucleolar transcription factor 1

1

0

High-throughput

0.279

Low

782186

BUD31
Protein BUD31 homolog

1

0

High-throughput

0.279

Low

918169

H4
Histone H4

1

0

High-throughput

0.279

Low

1022328

CSTF3
Cleavage stimulation factor subunit 3

1

0

High-throughput

0.279

Low

1040448

TRA2A
Transformer-2 protein homolog alpha

1

0

High-throughput

0.279

Low

1063695

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.279

Low

1129803

TDIF2
Deoxynucleotidyltransferase terminal-interacting protein 2

1

0

High-throughput

0.279

Low

1219330

PHF6
PHD finger protein 6

1

0

High-throughput

0.279

Low

1292689

DDX27
Probable ATP-dependent RNA helicase DDX27

1

0

High-throughput

0.279

Low

1292933

CP074
Uncharacterized protein C16orf74

1

0

High-throughput

0.279

Low

1313884

NOC4L
Nucleolar complex protein 4 homolog

1

0

High-throughput

0.279

Low

1329881

PININ
Pinin

1

0

High-throughput

0.279

Low

1333536

NOL11
Nucleolar protein 11

1

0

High-throughput

0.279

Low

1346304

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

0

High-throughput

0.279

Low

1377324

CHTOP
Chromatin target of PRMT1 protein

1

0

High-throughput

0.279

Low

1377326

SP16H
FACT complex subunit SPT16

1

0

High-throughput

0.279

Low

47328

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

336945

F13A
Coagulation factor XIII A chain

1

0

High-throughput

0.268

Low

363667

TTHY
Transthyretin

1

0

High-throughput

0.268

Low

584105

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

0

High-throughput

0.268

Low

1200936

Q86V38
Atrophin 1

1

0

High-throughput

0.268

Low

203817

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

0

High-throughput

0.265

Low

1133144

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.251

Low

1136702

H37
Histone H3-7

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024