HitPredict

Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: BAIP2 (Q9UQB8)
BAR/IMD domain-containing adapter protein 2 (Brain-specific angiogenesis inhibitor 1-associated protein 2) (BAI-associated protein 2) (BAI1-associated protein 2) (Protein BAP2) (Fas ligand-associated factor 3) (FLAF3) (Insulin receptor substrate p53/p58) (IRS-58) (IRSp53/58) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53)
Gene: BAIAP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH3_2, SH3_1~SH3_2, SH3_2~SH3_9
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008093 - cytoskeletal anchor activity
GO:0030838 - positive regulation of actin filament polymerization
GO:0097110 - scaffold protein binding
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 380
Hs

1 552
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024