HitPredict

Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: DLGP4 (Q9Y2H0)
Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4)
Gene: DLGAP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.561

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, mammalian protein protein interaction trap
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 380 Hs			1 992
+	Hs
		557837 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Hs
		145936 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		655514 P85A_HUMAN (166-379): 4.05e-24: 106: 16.36		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Hs
		412415 FYN_HUMAN (7-137): 2.1e-23: 103: 20.30		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Hs
		557812 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		924968 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Hs
		145955 ITSN2_HUMAN (3-309): 6.32e-28: 117: 18.31		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		145939 P85A_HUMAN (166-379): 4.05e-24: 106: 16.36		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		145934 FYN_HUMAN (7-137): 2.1e-23: 103: 20.30		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		327225 NCK1_HUMAN (1-379): 7.09e-91: 279: 68.24		DLGP3_HUMAN (1-992): 0: 986: 35.35
+	Hs
		145950 ITSN1_HUMAN (6-70): 3.77e-19: 91.7: 29.23		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		145943 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		145935 SRC_HUMAN (203-361): 5.72e-16: 81.3: 31.55		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Mm
		1246939 SH3K1_MOUSE (8-109): 3.82e-16: 82: 17.31		DLGP1_MOUSE (1-992): 0: 1144: 45.61
+	Hs
		655489 P85A_HUMAN (166-379): 4.05e-24: 106: 16.36		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		412385 FYN_HUMAN (7-137): 2.1e-23: 103: 20.30		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		924914 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		327228 P85A_HUMAN (166-379): 4.05e-24: 106: 16.36		DLGP3_HUMAN (1-992): 0: 986: 35.35
+	Hs
		327222 FYN_HUMAN (7-137): 2.1e-23: 103: 20.30		DLGP3_HUMAN (1-992): 0: 986: 35.35
+	Hs
		327232 GRB2_HUMAN (3-61): 2.24e-18: 84.7: 28.81		DLGP3_HUMAN (1-992): 0: 986: 35.35