Interactor 1: PLRG1 (O43660)
Pleiotropic regulator 1
Gene: PLRG1

Interactor 2: PRP8 (Q6P2Q9)
Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)
Gene: PRPF8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 28515276, 34079125
Identification Methods affinity chromatography technology, proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PRO8NT~WD40, PROCN~WD40, PRP8_domainIV~WD40
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016607 - nuclear speck
GO:0071007 - U2-type catalytic step 2 spliceosome
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 514
Hs

1 2335
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ Sc

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Last updated: 15 Jul 2024