Protein: CTBP
C-terminal-binding protein (CtBP protein) (dCtBP)

Gene: CTBP
Organism: Drosophila melanogaster
Interactions: 94
UniProt ID: O46036

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001221 - transcription coregulator binding
GO:0003713 - transcription coactivator activity
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

234437

CTBP
C-terminal-binding protein

3

15

Small-scale

0.843

High

234464

HLES
Protein hairless

7

1

Small-scale

0.744

High

234442

KNIR
Zygotic gap protein knirps

6

10

Small-scale

0.740

High

234441

SNAI
Protein snail

6

5

Small-scale

0.736

High

234445

HAIR
Protein hairy

5

3

Small-scale

0.725

High

234523

Q9XTN4
Brinker

3

1

Small-scale

0.687

High

234440

KRUP
Protein krueppel

3

3

Small-scale

0.635

High

234509

Q9VUK9
LD27370p

3

0

High-throughput

0.618

High

234459

EXD
Homeobox protein extradenticle

2

2

High-throughput

0.613

High

234462

UBX
Homeotic protein ultrabithorax

2

6

Small-scale

0.606

High

234454

ESCA
Protein escargot

2

5

Small-scale

0.600

High

234492

DANR
Protein distal antenna-related

2

1

Small-scale

0.600

High

234449

TLL
Protein tailless

2

9

High-throughput

0.594

High

234448

GROU
Protein groucho

2

9

Small-scale

0.584

High

234488

Q9V3B8
LD18634p

2

2

Small-scale

0.571

High

234503

Q9VNP3
Mesoderm-expressed 2, isoform B

2

1

High-throughput

0.571

High

234504

Q9VNP4
FI03846p

2

2

High-throughput

0.571

High

234513

Q9VWS1
Houki

2

1

High-throughput

0.571

High

234468

DIAP1
Death-associated inhibitor of apoptosis 1

1

6

Small-scale

0.561

High

54257

A1Z8F4
Schnurri, isoform D

2

0

Small-scale

0.559

High

234487

TIPT
Protein tiptop

1

4

Small-scale

0.552

High

234444

ESM8
Enhancer of split m8 protein

1

3

High-throughput

0.541

High

234456

PROS
Homeobox protein prospero

1

2

High-throughput

0.541

High

234467

HR78
Nuclear hormone receptor HR78

1

9

High-throughput

0.541

High

234473

Q59DN5
FI18025p1

1

11

High-throughput

0.541

High

234483

FOXO
Forkhead box protein O

1

9

High-throughput

0.541

High

234501

Q9VK36
Kumgang

1

1

High-throughput

0.541

High

234481

EBI
F-box-like/WD repeat-containing protein ebi

1

7

Small-scale

0.536

High

234465

Q0E8J0
MOG interacting and ectopic P-granules protein 1

1

0

Small-scale

0.513

High

234438

O46052
EG:152A3.3 protein

1

2

High-throughput

0.508

High

234443

KNRL
Knirps-related protein

1

12

High-throughput

0.508

High

234446

DORS
Embryonic polarity protein dorsal

1

7

High-throughput

0.508

High

234447

EGON
Protein embryonic gonad

1

11

High-throughput

0.508

High

234451

PABP
Polyadenylate-binding protein

1

3

High-throughput

0.508

High

234458

GIANT
Protein giant

1

3

High-throughput

0.508

High

234461

RB27C
Heterogeneous nuclear ribonucleoprotein 27C

1

6

High-throughput

0.508

High

234463

ESMD
Enhancer of split mdelta protein

1

3

Small-scale

0.508

High

234476

GLIS2
Zinc finger protein GLIS2 homolog

1

5

High-throughput

0.508

High

234482

Q95SH0
GH26463p

1

5

High-throughput

0.508

High

234494

Q9VFK4
NK7.1, isoform A

1

4

High-throughput

0.508

High

234500

Q9VJ55
Uncharacterized protein, isoform B

1

8

High-throughput

0.508

High

234520

Q9W3S4
LD46272p

1

1

High-throughput

0.508

High

234524

Q9Y1T2
Adenomatous polyposis coli 2

1

1

Small-scale

0.501

High

234453

DISC
Protein disconnected

1

0

High-throughput

0.486

High

234496

BCCIP
Protein BCCIP homolog

1

0

High-throughput

0.486

High

234507

Q9VTJ3
FI14630p

1

0

High-throughput

0.486

High

234515

Q9VYD4
GEO12007p1

1

0

High-throughput

0.486

High

234518

Q9W2E3
Negative cofactor 2alpha

1

0

High-throughput

0.486

High

234455

ABDA
Homeobox protein abdominal-A

1

8

High-throughput

0.481

High

68218

A8DYA3
Toutatis, isoform E

1

14

Small-scale

0.479

High

234439

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

3

Small-scale

0.479

High

234452

TSH
Protein teashirt

1

8

Small-scale

0.479

High

234469

DIAP2
Death-associated inhibitor of apoptosis 2

1

6

High-throughput

0.479

High

234471

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

3

Small-scale

0.479

High

234480

NFKB1
Nuclear factor NF-kappa-B p110 subunit

1

12

High-throughput

0.479

High

234486

GFI1
Zinc finger protein sens

1

3

Small-scale

0.479

High

234491

DAN
Protein distal antenna

1

1

Small-scale

0.479

High

234493

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

3

High-throughput

0.479

High

234502

KDM5
Lysine-specific demethylase 5

1

3

High-throughput

0.479

High

234521

Q9W410
PHD finger protein 12

1

6

High-throughput

0.479

High

234485

HRS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

5

High-throughput

0.464

High

234498

Q9VI72
Spindle assembly abnormal 4

1

4

High-throughput

0.464

High

234499

Q9VIE7
GMP synthase

1

1

High-throughput

0.464

High

234505

CH60B
60 kDa heat shock protein homolog 1, mitochondrial

1

1

High-throughput

0.464

High

234510

PYRG
CTP synthase

1

2

High-throughput

0.464

High

234511

Q9VVQ1
Allatostatin C receptor 1

1

1

High-throughput

0.464

High

234519

Q9W2J7
GH22922p

1

1

High-throughput

0.464

High

234470

EWG
DNA-binding protein Ewg

1

0

High-throughput

0.460

High

197552

PAX6
Paired box protein Pax-6

1

0

Small-scale

0.458

High

234478

Q8IQJ9
RE45537p

1

0

Small-scale

0.458

High

234516

Q9W1G7
LD21576p

1

0

High-throughput

0.458

High

234457

PDM1
Protein nubbin

1

4

High-throughput

0.445

High

234490

TRIB
Tribbles

1

3

High-throughput

0.445

High

118734

M9NFI9
Neurabin-1

1

7

High-throughput

0.442

High

234475

Q7JR58
Probable enoyl-CoA hydratase, mitochondrial

1

1

High-throughput

0.437

High

234489

Q9V3P3
LD45860p

1

0

High-throughput

0.426

High

234517

Q9W1L2
Uncharacterized protein, isoform A

1

1

High-throughput

0.417

High

234512

Q9VWI2
N(Alpha)-acetyltransferase 15/16, isoform A

1

5

High-throughput

0.407

High

234460

TTKA
Protein tramtrack, alpha isoform

1

7

High-throughput

0.381

High

234484

Q960G9
SD02279p

1

1

High-throughput

0.348

High

234472

Q4V664
IP05660p

1

0

High-throughput

0.265

Low

234479

GORAB
RAB6-interacting golgin

1

0

High-throughput

0.265

Low

234495

Q9VFN1
C2H2-type domain-containing protein

1

0

High-throughput

0.265

Low

234497

Q9VI16
Carnitine O-Acetyl-Transferase, isoform A

1

0

High-throughput

0.265

Low

234506

Q9VR29
RNA helicase

1

0

High-throughput

0.265

Low

234508

Q9VU89
RE10861p

1

0

High-throughput

0.265

Low

234522

TI50C
Mitochondrial import inner membrane translocase subunit TIM50-C

1

0

High-throughput

0.265

Low

234474

Q6NQZ7
LD40663p

1

0

High-throughput

0.249

Low

234477

IMD
Protein immune deficiency

1

0

High-throughput

0.249

Low

234514

PGPLE
Peptidoglycan-recognition protein LE

1

0

High-throughput

0.249

Low

57724

A1ZB77
Uncharacterized protein, isoform J

1

0

High-throughput

0.232

Low

234450

NRG
Neuroglian

1

0

High-throughput

0.232

Low

234466

Q0E8V7
Mitochondrial import inner membrane translocase subunit

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025