HitPredict

Interactor 1: PRC1 (O43663)
Protein regulator of cytokinesis 1
Gene: PRC1

Interactor 2: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.670

The method score is based on:

Property Details
Experiments 31586073, 17351640, 19468300
Identification Methods affinity chromatography technology, enzymatic study, far western blotting, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000922 - spindle pole
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005819 - spindle
and 6 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 620
Hs

1 603
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024