Interactor 1: GET3 (O43681)
ATPase GET3 (EC 3.6.-.-) (Arsenical pump-driving ATPase) (Arsenite-stimulated ATPase) (Guided entry of tail-anchored proteins factor 3, ATPase) (Transmembrane domain recognition complex 40 kDa ATPase subunit) (hARSA-I) (hASNA-I)
Gene: GET3

Interactor 2: GET4 (Q7L5D6)
Golgi to ER traffic protein 4 homolog (Conserved edge-expressed protein) (Transmembrane domain recognition complex 35 kDa subunit) (TRC35)
Gene: GET4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.962

The method score is based on:

Property Details
Experiments 26186194, 33961781, 34887561, 21516116, 32296183, 37071682, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, cross-linking study, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ArsA_ATPase~GET4
Common GO terms GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0006620 - post-translational protein targeting to endoplasmic reticulum membrane
GO:0045048 - protein insertion into ER membrane
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 348
Hs

1 327
+ Sp
+ Sc
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024