Interactor 1: BUB1 (O43683)
Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A)
Gene: BUB1

Interactor 2: CDC20 (Q12834)
Cell division cycle protein 20 homolog (p55CDC)
Gene: CDC20

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 26186194, 25669885, 26496610, 28514442, 26912231, 31118282, 33961781, 36736316, 25306918, 26811472, 23443559
Identification Methods affinity chromatography technology, unspecified method, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC4_WD40~Mad3_BUB1_I, Mad3_BUB1_I~WD40
Common GO terms GO:0000776 - kinetochore
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0007094 - mitotic spindle assembly checkpoint signaling
GO:0051301 - cell division
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1085
Hs

1 499
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Ce
+ Dm
+ Hs
+ Hs
+ Sc
+ Hs
+ At
+ At
+ At
+ At
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024