HitPredict

Interactor 1: BUB1 (O43683)
Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A)
Gene: BUB1

Interactor 2: CANB2 (Q96LZ3)
Calcineurin subunit B type 2 (Calcineurin B-like protein) (CBLP) (Calcineurin BII) (CNBII) (PPP3R1-like) (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform)
Gene: PPP3R2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	24412244
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	EF-hand_7~Pkinase
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1085 Hs			1 170
+	At
		989458 CDPK1_ARATH (664-1084): 5.91e-116: 373: 14.38		CDPK1_ARATH (6-169): 7e-42: 149: 25.15
+	At
		989461 KIN10_ARATH (786-1079): 4.93e-115: 367: 14.29		CDPK1_ARATH (6-169): 7e-42: 149: 25.15
+	At
		1104924 CDPK4_ARATH (756-1084): 9.47e-104: 336: 15.25		CDPK4_ARATH (6-161): 5.83e-42: 148: 28.13
+	At
		1105900 CDPKB_ARATH (755-1084): 8.27e-105: 339: 15.21		CDPKB_ARATH (6-161): 3.44e-41: 145: 28.13
+	Hs
		325646 LATS1_HUMAN (111-1077): 6.55e-119: 395: 10.17		HPCL1_HUMAN (35-153): 5.11e-17: 76.3: 36.64
+	Hs
		160718 AURKA_HUMAN (654-1065): 8.12e-81: 271: 15.09		CANB2_HUMAN (1-170): 1.72e-45: 148: 100.00
+	Hs
		483929 KCC1A_HUMAN (778-1084): 3.86e-115: 362: 14.20		CALM1_HUMAN (16-82): 5.7e-10: 56.4: 28.17
+	Hs
		648500 KCC1A_HUMAN (778-1084): 3.86e-115: 362: 14.20		CALL3_HUMAN (83-159): 2.2e-09: 54.9: 24.68
+	Hs
		483947 KCC1D_HUMAN (767-1084): 3.33e-114: 360: 15.55		CALM1_HUMAN (16-82): 5.7e-10: 56.4: 28.17
+	Hs
		648542 KCC1D_HUMAN (767-1084): 3.33e-114: 360: 15.55		CALL3_HUMAN (83-159): 2.2e-09: 54.9: 24.68
+	Gm
		1196117 Q84P28_SOYBN (785-1084): 3.07e-104: 338: 15.43		Q84P28_SOYBN (14-101): 2.17e-10: 59.9: 21.51
+	At
		976699 CDPKU_ARATH (740-1085): 2.99e-105: 342: 16.71		CALM6_ARATH (16-82): 7.36e-09: 53.7: 28.17
+	At
		886638 CDPKU_ARATH (740-1085): 2.99e-105: 342: 16.71		CALM7_ARATH (80-159): 7.74e-09: 53.4: 27.50
+	At
		483177 CDPKU_ARATH (740-1085): 2.99e-105: 342: 16.71		CALM4_ARATH (16-82): 9.82e-09: 53.3: 28.17
+	Hs
		483928 KCC2D_HUMAN (774-1085): 1.18e-103: 336: 14.29		CALM1_HUMAN (16-82): 5.7e-10: 56.4: 28.17
+	Hs
		484002 KCC2D_HUMAN (774-1085): 1.18e-103: 336: 14.29		CALM2_HUMAN (16-82): 5.7e-10: 56.4: 28.17
+	Hs
		484120 KCC2D_HUMAN (774-1085): 1.18e-103: 336: 14.29		CALM3_HUMAN (16-82): 5.7e-10: 56.4: 28.17
+	Dm
		906661 KCC2A_DROME (784-1085): 7.2e-77: 264: 15.06		CALM_DROME (16-82): 8.63e-10: 56: 28.17