HitPredict

Interactor 1: BUB3 (O43684)
Mitotic checkpoint protein BUB3
Gene: BUB3

Interactor 2: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37827155, 24332808
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0051321 - meiotic cell cycle
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 328 Hs			1 616
+	Hs
		652407 NLE1_HUMAN (86-326): 2.9e-49: 172: 13.10		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		154656 GNB5_HUMAN (13-206): 2.53e-26: 109: 22.06		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		651925 SNR40_HUMAN (1-121): 1.07e-23: 101: 17.42		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		650859 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Zm
		26730 B4FKM1_MAIZE (91-295): 1.34e-09: 60.5: 15.56		A0A1D6J7G3_MAIZE (151-597): 2.86e-113: 350: 17.92
+	Zm
		16354 A0A1D6IXS6_MAIZE (181-319): 9.53e-16: 80.2: 13.57		A0A1D6GLY8_MAIZE (327-580): 4.48e-48: 174: 16.98