HitPredict

Interactor 1: BUB3 (O43684)
Mitotic checkpoint protein BUB3
Gene: BUB3

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	15388328
Identification Methods	biochemical, affinity chromatography technology
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 328 Hs			1 488
+	Hs
		211173 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1270358 FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1270370 SNR40_HUMAN (1-121): 1.07e-23: 101: 17.42		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		903404 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		903202 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		177249 WDR5_HUMAN (209-320): 6.93e-20: 90.4: 16.07		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Dm
		1182201 EBI_DROME (1-86): 1.34e-17: 85.4: 18.39		Q7KTS4_DROME (10-430): 0: 560: 57.11
+	Dm
		1279322 EBI_DROME (1-86): 1.34e-17: 85.4: 18.39		Q9VNC2_DROME (10-430): 0: 556: 56.88
+	Hs
		211269 BUB3_HUMAN (1-328): 4.65e-94: 284: 100.00		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Hs
		1260173 FBXW7_HUMAN (1-202): 6.93e-47: 169: 20.85		HDAC7_HUMAN (29-280): 1.96e-23: 106: 26.37