Protein: CASPC
Inactive caspase-12 (CASP-12)

Gene: CASPC, CASP12
Organism: Homo sapiens
Interactions: 20
UniProt ID: Q6UXS9

Gene Ontology (top 5):
GO:0004197 - cysteine-type endopeptidase activity
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0006508 - proteolysis
GO:0043525 - positive regulation of neuron apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1166742

CASPC
Inactive caspase-12

2

18

Small-scale

0.768

High

876988

CASP9
Caspase-9

1

20

Small-scale

0.647

High

201809

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

1

8

Small-scale

0.618

High

957725

XIAP
E3 ubiquitin-protein ligase XIAP

1

20

Small-scale

0.618

High

1166744

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

20

Small-scale

0.618

High

282683

RNF8
E3 ubiquitin-protein ligase RNF8

1

5

High-throughput

0.553

High

795766

MAGA3
Melanoma-associated antigen 3

1

1

Small-scale

0.552

High

896323

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

1

Small-scale

0.501

High

347111

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.500

High

786374

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

2

High-throughput

0.500

High

359033

CRYAB
Alpha-crystallin B chain

1

10

Small-scale

0.479

High

502243

BIP
Endoplasmic reticulum chaperone BiP

1

6

Small-scale

0.479

High

734663

TRI23
E3 ubiquitin-protein ligase TRIM23

1

1

High-throughput

0.479

High

1020747

TRAF2
TNF receptor-associated factor 2

1

19

Small-scale

0.479

High

545990

MYOD1
Myoblast determination protein 1

1

1

High-throughput

0.457

High

529301

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.445

High

379526

MYCN
N-myc proto-oncogene protein

1

6

High-throughput

0.437

High

1166745

TRRAP
Transformation/transcription domain-associated protein

1

2

High-throughput

0.437

High

1166743

NEK10
Serine/threonine-protein kinase Nek10

1

5

High-throughput

0.407

High


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Last updated: 15 Jul 2024