Interactor 1: ACTN4 (O43707)
Alpha-actinin-4 (Non-muscle alpha-actinin 4)
Gene: ACTN4

Interactor 2: CADH1 (P12830)
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]
Gene: CDH1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.51 0.60 0.554

The method score is based on:

Property Details
Experiments 16212417
Identification Methods affinity chromatography technology, surface plasmon resonance, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0015629 - actin cytoskeleton
GO:0030054 - cell junction
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 911
Hs

1 882
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024