HitPredict

Interactor 1: HTSF1 (O43719)
17S U2 SnRNP complex component HTATSF1 (HIV Tat-specific factor 1) (Tat-SF1)
Gene: HTATSF1

Interactor 2: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35987950
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 755 Hs			1 465
+	Hs
		227642 PAP1L_HUMAN (62-277): 7.36e-37: 149: 11.77		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		228318 PABP5_HUMAN (118-346): 2.01e-38: 148: 19.83		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		226572 U2AF2_HUMAN (129-356): 2.97e-32: 133: 22.03		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227354 PABP4_HUMAN (62-285): 4.99e-31: 131: 12.66		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		226635 TIA1_HUMAN (127-364): 1.82e-31: 129: 16.12		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		228678 PABP3_HUMAN (62-292): 3.04e-30: 129: 11.72		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		226375 PABP1_HUMAN (62-264): 9.56e-30: 127: 12.14		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227552 ELAV1_HUMAN (133-381): 1.21e-29: 122: 15.69		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227204 EWS_HUMAN (126-217): 8.36e-16: 83.3: 26.60		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		226687 FUS_HUMAN (110-216): 7.15e-11: 67.5: 24.07		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		1031383 PABP4_HUMAN (62-285): 4.99e-31: 131: 12.66		CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58
+	Hs
		312484 U2AF2_HUMAN (129-356): 2.97e-32: 133: 22.03		ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82
+	Hs
		312493 TIA1_HUMAN (127-364): 1.82e-31: 129: 16.12		ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82
+	Hs
		312462 PABP1_HUMAN (62-264): 9.56e-30: 127: 12.14		ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82
+	Hs
		312578 EWS_HUMAN (126-217): 8.36e-16: 83.3: 26.60		ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82
+	At
		186465 PABP4_ARATH (133-496): 3.71e-34: 141: 11.08		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17
+	At
		983451 PABP5_ARATH (131-500): 2.82e-33: 138: 11.97		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17
+	Hs
		475708 PABP4_HUMAN (62-285): 4.99e-31: 131: 12.66		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		475288 PABP1_HUMAN (62-264): 9.56e-30: 127: 12.14		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		475809 ELAV1_HUMAN (133-381): 1.21e-29: 122: 15.69		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47