Protein: CLN6
Ceroid-lipofuscinosis neuronal protein 6 (Protein CLN6)

Gene: CLN6
Organism: Homo sapiens
Interactions: 125
UniProt ID: Q9NWW5

Gene Ontology (top 5):
GO:0001573 - ganglioside metabolic process
GO:0005730 - nucleolus
GO:0005769 - early endosome
GO:0005783 - endoplasmic reticulum
GO:0005788 - endoplasmic reticulum lumen

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

516156

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.580

High

798224

KI2L3
Killer cell immunoglobulin-like receptor 2DL3

2

0

High-throughput

0.580

High

1134994

GORAB
RAB6-interacting golgin

2

0

High-throughput

0.580

High

1190960

RIC3
Protein RIC-3

2

0

High-throughput

0.580

High

1192792

CPLX4
Complexin-4

2

0

High-throughput

0.580

High

1217225

TM139
Transmembrane protein 139

2

0

High-throughput

0.580

High

1232090

LRC25
Leucine-rich repeat-containing protein 25

2

0

High-throughput

0.580

High

1234740

CISD2
CDGSH iron-sulfur domain-containing protein 2

2

0

High-throughput

0.580

High

1252740

FNDC9
Fibronectin type III domain-containing protein 9

2

0

High-throughput

0.580

High

1285285

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

0

High-throughput

0.580

High

1300160

TM237
Transmembrane protein 237

2

0

High-throughput

0.580

High

1309351

CYBC1
Cytochrome b-245 chaperone 1

2

0

High-throughput

0.580

High

1347539

TX264
Testis-expressed protein 264

2

0

High-throughput

0.580

High

178016

TMPS2
Transmembrane protease serine 2

2

2

High-throughput

0.553

High

1307266

RNF5
E3 ubiquitin-protein ligase RNF5

2

0

Small-scale

0.547

High

172256

GP182
G-protein coupled receptor 182

1

0

High-throughput

0.513

High

487062

LYAG
Lysosomal alpha-glucosidase

1

0

High-throughput

0.513

High

735023

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

0

High-throughput

0.513

High

1033579

ILK
Integrin-linked protein kinase

1

0

High-throughput

0.513

High

1161913

NCEH1
Neutral cholesterol ester hydrolase 1

1

0

High-throughput

0.513

High

1233055

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.513

High

1253912

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.513

High

1266047

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

1332026

SG196
Protein O-mannose kinase

1

0

High-throughput

0.513

High

1347536

PCDB3
Protocadherin beta-3

1

0

High-throughput

0.513

High

385609

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.500

High

987300

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

1

High-throughput

0.500

High

125757

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.493

High

1330331

TMPS5
Transmembrane protease serine 5

1

2

High-throughput

0.489

High

455932

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

1132457

MARH8
E3 ubiquitin-protein ligase MARCHF8

1

1

High-throughput

0.479

High

1198696

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

1

High-throughput

0.479

High

1345074

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.479

High

1347533

AMFR
E3 ubiquitin-protein ligase AMFR

1

2

High-throughput

0.479

High

154640

TPP1
Tripeptidyl-peptidase 1

1

0

Small-scale

0.458

High

206055

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

267260

CLN5
Bis(monoacylglycero)phosphate synthase CLN5

1

0

Small-scale

0.458

High

359080

CRYAB
Alpha-crystallin B chain

1

0

Small-scale

0.458

High

504852

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

750500

COIL
Coilin

1

0

High-throughput

0.458

High

842394

PPT1
Palmitoyl-protein thioesterase 1

1

0

Small-scale

0.458

High

875363

TERA
Transitional endoplasmic reticulum ATPase

1

0

Small-scale

0.458

High

918034

H4
Histone H4

1

0

High-throughput

0.458

High

1053220

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

0

High-throughput

0.458

High

1087988

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

0

High-throughput

0.458

High

1168708

SYNE3
Nesprin-3

1

0

High-throughput

0.458

High

1188412

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

1284113

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1305537

CGRF1
Cell growth regulator with RING finger domain protein 1

1

0

High-throughput

0.458

High

1313077

DERL1
Derlin-1

1

0

Small-scale

0.458

High

1081624

NTRK3
NT-3 growth factor receptor

1

1

High-throughput

0.457

High

163365

XPO1
Exportin-1

1

1

Small-scale

0.445

High

266262

ERLN1
Erlin-1

1

1

Small-scale

0.445

High

299998

ERLN2
Erlin-2

1

1

Small-scale

0.445

High

787585

MTOR
Serine/threonine-protein kinase mTOR

1

1

Small-scale

0.445

High

883654

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.445

High

1268268

GCN1
Stalled ribosome sensor GCN1

1

1

Small-scale

0.445

High

587723

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

2

High-throughput

0.437

High

718244

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.437

High

1304138

RING2
E3 ubiquitin-protein ligase RING2

1

1

High-throughput

0.437

High

1330862

Q9H4D1
Protein kinase

1

1

High-throughput

0.437

High

1347530

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

1

High-throughput

0.437

High

1347531

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

1

High-throughput

0.437

High

156567

SCAM3
Secretory carrier-associated membrane protein 3

1

0

Small-scale

0.426

High

239284

ICMT
Protein-S-isoprenylcysteine O-methyltransferase

1

0

Small-scale

0.426

High

260209

MPU1
Mannose-P-dolichol utilization defect 1 protein

1

0

Small-scale

0.426

High

303967

YIF1A
Protein YIF1A

1

0

Small-scale

0.426

High

354582

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.426

High

561696

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

0

Small-scale

0.426

High

706735

MRP1
Multidrug resistance-associated protein 1

1

0

Small-scale

0.426

High

763115

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

Small-scale

0.426

High

809988

STT3A
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

1

0

Small-scale

0.426

High

867015

MOT1
Monocarboxylate transporter 1

1

0

Small-scale

0.426

High

966126

LAT1
Large neutral amino acids transporter small subunit 1

1

0

Small-scale

0.426

High

1233973

EMC5
ER membrane protein complex subunit 5

1

0

Small-scale

0.426

High

1252091

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

0

Small-scale

0.426

High

1305455

CHP1
Calcineurin B homologous protein 1

1

0

Small-scale

0.426

High

1336696

TM9S3
Transmembrane 9 superfamily member 3

1

0

Small-scale

0.426

High

1347527

CLN6
Ceroid-lipofuscinosis neuronal protein 6

1

0

Small-scale

0.426

High

1347528

NSMA3
Sphingomyelin phosphodiesterase 4

1

0

Small-scale

0.426

High

1347535

TELO2
Telomere length regulation protein TEL2 homolog

1

0

Small-scale

0.426

High

1347538

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

0

Small-scale

0.426

High

1347532

XPO7
Exportin-7

1

1

Small-scale

0.407

High

49751

S22AN
Solute carrier family 22 member 23

2

0

High-throughput

0.316

High

132612

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

2

0

High-throughput

0.316

High

157144

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

2

0

High-throughput

0.316

High

315160

CLD7
Claudin-7

2

0

High-throughput

0.316

High

713750

EVI2B
Protein EVI2B

2

0

High-throughput

0.316

High

816661

CXA8
Gap junction alpha-8 protein

2

0

High-throughput

0.316

High

1083999

STX1A
Syntaxin-1A

2

0

High-throughput

0.316

High

1110108

AR13B
ADP-ribosylation factor-like protein 13B

2

0

High-throughput

0.316

High

1128739

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

1216654

CLC10
C-type lectin domain family 10 member A

2

0

High-throughput

0.316

High

1330472

LIME1
Lck-interacting transmembrane adapter 1

2

0

High-throughput

0.316

High

1234567

SH2D3
SH2 domain-containing protein 3C

2

0

High-throughput

0.298

High

156948

FFAR1
Free fatty acid receptor 1

1

0

High-throughput

0.279

Low

328402

S1PR4
Sphingosine 1-phosphate receptor 4

1

0

High-throughput

0.279

Low

686399

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

0

High-throughput

0.279

Low

702424

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

0

High-throughput

0.279

Low

819072

AL3B2
Aldehyde dehydrogenase family 3 member B2

1

0

High-throughput

0.279

Low

1165181

I27RA
Interleukin-27 receptor subunit alpha

1

0

High-throughput

0.279

Low

1218246

NNRD
ATP-dependent

1

0

High-throughput

0.279

Low

1219057

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

1254674

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1299260

OPALI
Opalin

1

0

High-throughput

0.279

Low

1329631

KLK15
Kallikrein-15

1

0

High-throughput

0.279

Low

1347534

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

0

High-throughput

0.279

Low

1347537

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.279

Low

665669

EPHB2
Ephrin type-B receptor 2

1

0

High-throughput

0.268

Low

360477

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.251

Low

553878

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

652416

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

721606

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

780201

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

824449

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

828402

CENPA
Histone H3-like centromeric protein A

1

0

High-throughput

0.249

Low

909217

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

1088243

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

0

High-throughput

0.249

Low

1188943

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1297993

KCTD7
BTB/POZ domain-containing protein KCTD7

1

0

Small-scale

0.249

Low

1330948

RHOJ
Rho-related GTP-binding protein RhoJ

1

0

High-throughput

0.249

Low

1332679

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

1314487

IFT27
Intraflagellar transport protein 27 homolog

1

0

High-throughput

0.232

Low

1347529

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024