Protein: GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5 (Glycerophosphocholine phosphodiesterase GDPD5) (EC 3.1.4.2) (Glycerophosphodiester phosphodiesterase 2) (Phosphoinositide phospholipase C GDPD5) (EC 3.1.4.11)

Gene: GDPD5
Organism: Homo sapiens
Interactions: 119
UniProt ID: Q8WTR4

Gene Ontology (top 5):
GO:0004435 - phosphatidylinositol-4,5-bisphosphate phospholipase C activity
GO:0005886 - plasma membrane
GO:0006629 - lipid metabolic process
GO:0007399 - nervous system development
GO:0008889 - glycerophosphodiester phosphodiesterase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

189736

STX7
Syntaxin-7

3

5

High-throughput

0.662

High

1326563

PP4P2
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

3

1

High-throughput

0.662

High

1355916

IGSF8
Immunoglobulin superfamily member 8

3

1

High-throughput

0.662

High

1355948

STX8
Syntaxin-8

3

2

High-throughput

0.662

High

295857

FACE1
CAAX prenyl protease 1 homolog

3

0

High-throughput

0.634

High

1355954

ROBO1
Roundabout homolog 1

3

0

High-throughput

0.634

High

1355934

GPC5C
G-protein coupled receptor family C group 5 member C

2

1

High-throughput

0.628

High

1238357

RETST
All-trans-retinol 13,14-reductase

3

1

High-throughput

0.604

High

1129214

KCJ11
ATP-sensitive inward rectifier potassium channel 11

2

0

High-throughput

0.602

High

1355914

EDA
Ectodysplasin-A

2

0

High-throughput

0.602

High

1355928

SGPP1
Sphingosine-1-phosphate phosphatase 1

2

0

High-throughput

0.602

High

1355942

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

2

0

High-throughput

0.602

High

160906

STX16
Syntaxin-16

2

5

High-throughput

0.601

High

1151600

TRIP6
Thyroid receptor-interacting protein 6

2

0

High-throughput

0.588

High

1355926

NDC1
Nucleoporin NDC1

2

0

High-throughput

0.576

High

1355938

ZDH18
Palmitoyltransferase ZDHHC18

2

2

High-throughput

0.574

High

1355950

ZDHC9
Palmitoyltransferase ZDHHC9

2

2

High-throughput

0.574

High

1307756

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

1

High-throughput

0.573

High

213333

ADCY6
Adenylate cyclase type 6

1

1

High-throughput

0.536

High

537587

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.536

High

931021

HSP72
Heat shock-related 70 kDa protein 2

1

2

High-throughput

0.536

High

1129843

EPN4
Clathrin interactor 1

1

0

High-throughput

0.518

High

1355929

KPCD2
Serine/threonine-protein kinase D2

1

0

High-throughput

0.513

High

1355946

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.513

High

1258455

CHSS3
Chondroitin sulfate synthase 3

1

2

High-throughput

0.489

High

1355925

AASD1
Alanyl-tRNA editing protein Aarsd1

1

1

High-throughput

0.489

High

180559

PLS1
Phospholipid scramblase 1

1

1

High-throughput

0.481

High

332681

LYPD3
Ly6/PLAUR domain-containing protein 3

1

0

High-throughput

0.458

High

125773

STXB3
Syntaxin-binding protein 3

1

1

High-throughput

0.445

High

163333

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

1

High-throughput

0.445

High

249883

STX10
Syntaxin-10

1

2

High-throughput

0.445

High

689839

CD27
CD27 antigen

1

1

High-throughput

0.445

High

770808

HRH1
Histamine H1 receptor

1

2

High-throughput

0.445

High

1083195

GALT1
Polypeptide N-acetylgalactosaminyltransferase 1

1

1

High-throughput

0.445

High

1087214

STX4
Syntaxin-4

1

4

High-throughput

0.445

High

1097849

STX5
Syntaxin-5

1

6

High-throughput

0.445

High

1100699

STX3
Syntaxin-3

1

4

High-throughput

0.445

High

1286696

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

1

High-throughput

0.445

High

1294800

STX12
Syntaxin-12

1

5

High-throughput

0.445

High

1335808

GALT6
Polypeptide N-acetylgalactosaminyltransferase 6

1

1

High-throughput

0.445

High

1339273

RAI3
Retinoic acid-induced protein 3

1

1

High-throughput

0.445

High

1355918

PCFT
Proton-coupled folate transporter

1

1

High-throughput

0.445

High

1355931

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

1

High-throughput

0.445

High

124081

SNP23
Synaptosomal-associated protein 23

1

0

High-throughput

0.426

High

483938

HMOX1
Heme oxygenase 1

1

0

High-throughput

0.426

High

484189

PGFRB
Platelet-derived growth factor receptor beta

1

0

High-throughput

0.426

High

618273

CADH2
Cadherin-2

1

0

High-throughput

0.426

High

687118

MGAT1
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

0

High-throughput

0.426

High

878064

AGRE5
Adhesion G protein-coupled receptor E5

1

0

High-throughput

0.426

High

890022

PSN1
Presenilin-1

1

0

High-throughput

0.426

High

1022922

EFNB1
Ephrin-B1

1

0

High-throughput

0.426

High

1089989

LMAN2
Vesicular integral-membrane protein VIP36

1

0

High-throughput

0.426

High

1133221

STAR3
StAR-related lipid transfer protein 3

1

0

High-throughput

0.426

High

1144640

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

0

High-throughput

0.426

High

1355913

PIEZ1
Piezo-type mechanosensitive ion channel component 1

1

0

High-throughput

0.426

High

1355923

YIPF4
Protein YIPF4

1

0

High-throughput

0.426

High

1355924

SYT11
Synaptotagmin-11

1

0

High-throughput

0.426

High

212082

B4GT5
Beta-1,4-galactosyltransferase 5

1

1

High-throughput

0.407

High

611250

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

1

High-throughput

0.407

High

1085351

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

1

High-throughput

0.407

High

1329287

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

1

1

High-throughput

0.407

High

1355930

GL8D2
Glycosyltransferase 8 domain-containing protein 2

1

1

High-throughput

0.407

High

1355936

VPS45
Vacuolar protein sorting-associated protein 45

1

1

High-throughput

0.407

High

1355937

C1GLT
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

1

1

High-throughput

0.407

High

1355941

B4GT7
Beta-1,4-galactosyltransferase 7

1

1

High-throughput

0.407

High

1355943

SEC63
Translocation protein SEC63 homolog

1

1

High-throughput

0.407

High

1355947

ZDHC8
Palmitoyltransferase ZDHHC8

1

3

High-throughput

0.407

High

209796

NDUS4
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

3

0

High-throughput

0.345

High

847425

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

3

0

High-throughput

0.345

High

975556

SELT
Thioredoxin reductase-like selenoprotein T

3

0

High-throughput

0.345

High

1335142

LEMD2
LEM domain-containing protein 2

3

0

High-throughput

0.345

High

1355915

SCAM4
Secretory carrier-associated membrane protein 4

3

0

High-throughput

0.345

High

1355939

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

3

0

High-throughput

0.345

High

1355945

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

3

0

High-throughput

0.345

High

1355953

TX264
Testis-expressed protein 264

3

0

High-throughput

0.345

High

506630

GPHRB
Golgi pH regulator B

3

0

High-throughput

0.335

High

136529

GOLI4
Golgi integral membrane protein 4

2

0

High-throughput

0.328

High

1217650

MARC1
Mitochondrial amidoxime-reducing component 1

2

0

High-throughput

0.328

High

1355912

THEM6
Protein THEM6

2

0

High-throughput

0.328

High

1355920

PIGQ
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q

2

0

High-throughput

0.328

High

1355927

CA043
Protein C1orf43

2

0

High-throughput

0.328

High

1248353

TM205
Transmembrane protein 205

2

0

High-throughput

0.313

High

1244047

KR261
Keratin-associated protein 26-1

2

0

High-throughput

0.300

High

896275

PEX5
Peroxisomal targeting signal 1 receptor

1

0

High-throughput

0.299

High

278703

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

0

High-throughput

0.279

Low

1272406

GET4
Golgi to ER traffic protein 4 homolog

1

0

High-throughput

0.279

Low

1355917

KLH15
Kelch-like protein 15

1

0

High-throughput

0.279

Low

1355922

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.279

Low

1355932

TM9S3
Transmembrane 9 superfamily member 3

1

0

High-throughput

0.279

Low

1355935

PRDM5
PR domain zinc finger protein 5

1

0

High-throughput

0.279

Low

1355949

RUVB2
RuvB-like 2

1

0

High-throughput

0.279

Low

789936

FDFT
Squalene synthase

1

0

High-throughput

0.269

Low

49676

T120B
Transmembrane protein 120B

1

0

High-throughput

0.232

Low

223852

NDUA2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

1

0

High-throughput

0.232

Low

250941

TPST1
Protein-tyrosine sulfotransferase 1

1

0

High-throughput

0.232

Low

316538

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

1

0

High-throughput

0.232

Low

331904

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.232

Low

638131

AOFA
Amine oxidase [flavin-containing] A

1

0

High-throughput

0.232

Low

773939

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.232

Low

814833

CUX1
Homeobox protein cut-like 1

1

0

High-throughput

0.232

Low

1164143

CP51A
Lanosterol 14-alpha demethylase

1

0

High-throughput

0.232

Low

1210404

MANEA
Glycoprotein endo-alpha-1,2-mannosidase

1

0

High-throughput

0.232

Low

1233994

ASPH2
Aspartate beta-hydroxylase domain-containing protein 2

1

0

High-throughput

0.232

Low

1238659

TM214
Transmembrane protein 214

1

0

High-throughput

0.232

Low

1251336

DJC14
DnaJ homolog subfamily C member 14

1

0

High-throughput

0.232

Low

1254298

TMPPE
Transmembrane protein with metallophosphoesterase domain

1

0

High-throughput

0.232

Low

1287760

NOP9
Nucleolar protein 9

1

0

High-throughput

0.232

Low

1307546

ZDH13
Palmitoyltransferase ZDHHC13

1

0

High-throughput

0.232

Low

1309856

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.232

Low

1327314

FBCD1
Fibrinogen C domain-containing protein 1

1

0

High-throughput

0.232

Low

1330327

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.232

Low

1332739

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.232

Low

1355919

PIGS
GPI-anchor transamidase component PIGS

1

0

High-throughput

0.232

Low

1355921

MXRA8
Matrix remodeling-associated protein 8

1

0

High-throughput

0.232

Low

1355933

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

1

0

High-throughput

0.232

Low

1355940

EXTL2
Exostosin-like 2

1

0

High-throughput

0.232

Low

1355944

SUN2
SUN domain-containing protein 2

1

0

High-throughput

0.232

Low

1355951

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.232

Low

1355952

ALG5
Dolichyl-phosphate beta-glucosyltransferase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025