HitPredict

Interactor 1: HTSF1 (O43719)
17S U2 SnRNP complex component HTATSF1 (HIV Tat-specific factor 1) (Tat-SF1)
Gene: HTATSF1

Interactor 2: DYRK2 (Q92630)
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)
Gene: DYRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 755 Hs			1 601
+	At
		621700 RB45A_ARATH (31-400): 4.79e-61: 212: 11.74		CDKA1_ARATH (219-538): 8.93e-128: 379: 24.77
+	Hs
		625400 ELAV2_HUMAN (117-424): 7.45e-35: 138: 13.06		CDK2_HUMAN (219-543): 6.32e-142: 415: 27.71
+	Hs
		516362 PABP1_HUMAN (62-264): 9.56e-30: 127: 12.14		CDK2_HUMAN (219-543): 6.32e-142: 415: 27.71
+	Hs
		212115 HTSF1_HUMAN (1-755): 2.64e-92: 306: 100.00		CLK1_HUMAN (204-535): 3.1e-62: 215: 35.80
+	Mm
		554885 TIA1_MOUSE (127-376): 1.76e-31: 129: 15.75		KPCE_MOUSE (55-510): 2.32e-124: 385: 16.70
+	Hs
		642764 ELAV4_HUMAN (88-420): 8.56e-36: 141: 13.20		DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52
+	Hs
		1020254 ELAV2_HUMAN (117-424): 7.45e-35: 138: 13.06		DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52
+	Hs
		969086 ELAV1_HUMAN (133-381): 1.21e-29: 122: 15.69		KPCE_HUMAN (55-510): 3.31e-123: 382: 16.70
+	Hs
		1031320 PABP4_HUMAN (62-285): 4.99e-31: 131: 12.66		DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52
+	Hs
		414931 ELAV1_HUMAN (133-381): 1.21e-29: 122: 15.69		CDK1_HUMAN (219-538): 9.81e-126: 373: 27.13
+	Hs
		516508 PABP1_HUMAN (62-264): 9.56e-30: 127: 12.14		DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52
+	Hs
		1043817 ELAV1_HUMAN (133-381): 1.21e-29: 122: 15.69		DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52
+	Hs
		625178 FUS_HUMAN (110-216): 7.15e-11: 67.5: 24.07		CDK2_HUMAN (219-543): 6.32e-142: 415: 27.71
+	Sc
		376610 PABP_YEAST (62-422): 9.79e-26: 114: 13.46		YAK1_YEAST (117-573): 7.71e-111: 352: 32.27
+	Hs
		726806 FUS_HUMAN (110-216): 7.15e-11: 67.5: 24.07		DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52
+	Hs
		833945 PABP5_HUMAN (118-346): 2.01e-38: 148: 19.83		CLK2_HUMAN (204-543): 6.41e-57: 201: 31.56
+	Hs
		833874 ELAV2_HUMAN (117-424): 7.45e-35: 138: 13.06		CLK2_HUMAN (204-543): 6.41e-57: 201: 31.56
+	Hs
		641666 U2AF2_HUMAN (129-356): 2.97e-32: 133: 22.03		CLK2_HUMAN (204-543): 6.41e-57: 201: 31.56
+	Hs
		516416 PABP1_HUMAN (62-264): 9.56e-30: 127: 12.14		CLK2_HUMAN (204-543): 6.41e-57: 201: 31.56