Protein: MDN1
Midasin (Dynein-related AAA-ATPase MDN1) (MIDAS-containing protein)

Gene: MDN1
Organism: Homo sapiens
Interactions: 232
UniProt ID: Q9NU22

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0000055 - ribosomal large subunit export from nucleus
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

218832

TGON2
Trans-Golgi network integral membrane protein 2

4

8

High-throughput

0.691

High

774660

BASI
Basigin

3

5

High-throughput

0.667

High

1328630

PAR16
Protein mono-ADP-ribosyltransferase PARP16

3

1

High-throughput

0.667

High

373266

MYC
Myc proto-oncogene protein

3

11

High-throughput

0.640

High

1137174

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

3

2

High-throughput

0.640

High

1293916

VSIG1
V-set and immunoglobulin domain-containing protein 1

3

1

High-throughput

0.604

High

964475

SUMO2
Small ubiquitin-related modifier 2

2

3

High-throughput

0.602

High

596786

DPEP1
Dipeptidase 1

2

0

High-throughput

0.602

High

50708

HACL2
2-hydroxyacyl-CoA lyase 2

2

1

High-throughput

0.601

High

831507

CCNF
Cyclin-F

2

3

High-throughput

0.601

High

1209712

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

8

Small-scale

0.601

High

260517

BRD4
Bromodomain-containing protein 4

2

14

High-throughput

0.584

High

302646

RNF8
E3 ubiquitin-protein ligase RNF8

2

5

Small-scale

0.584

High

980412

H4
Histone H4

2

12

High-throughput

0.584

High

1114421

CUL3
Cullin-3

2

10

High-throughput

0.584

High

1436810

WDR76
WD repeat-containing protein 76

2

16

High-throughput

0.584

High

1449705

NLE1
Notchless protein homolog 1

2

12

Small-scale

0.584

High

1449713

DKKL1
Dickkopf-like protein 1

2

1

High-throughput

0.574

High

397036

ESR1
Estrogen receptor

2

18

High-throughput

0.571

High

1101678

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

2

4

High-throughput

0.549

High

1412032

WDR83
WD repeat domain-containing protein 83

2

14

High-throughput

0.549

High

1449708

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

2

1

High-throughput

0.549

High

1449724

NPTN
Neuroplastin

2

5

High-throughput

0.549

High

182796

GP182
G-protein coupled receptor 182

1

6

High-throughput

0.536

High

316633

ST17B
Serine/threonine-protein kinase 17B

1

8

High-throughput

0.536

High

457733

TBB5
Tubulin beta chain

1

2

High-throughput

0.536

High

564436

CFTR
Cystic fibrosis transmembrane conductance regulator

1

7

High-throughput

0.536

High

857572

NOTC1
Neurogenic locus notch homolog protein 1

1

7

High-throughput

0.536

High

872786

SOX2
Transcription factor SOX-2

1

6

High-throughput

0.536

High

891328

GSK3A
Glycogen synthase kinase-3 alpha

1

19

High-throughput

0.536

High

1038480

TIE2
Angiopoietin-1 receptor

1

10

High-throughput

0.536

High

1091357

FOXL1
Forkhead box protein L1

1

5

High-throughput

0.536

High

1111302

SNW1
SNW domain-containing protein 1

1

3

High-throughput

0.536

High

1126769

BECN1
Beclin-1

1

2

High-throughput

0.536

High

1310457

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.536

High

1383871

EFMT3
EEF1A lysine methyltransferase 3

1

9

High-throughput

0.536

High

1387277

HDA11
Histone deacetylase 11

1

11

High-throughput

0.536

High

1402720

TCPQM
T-complex protein 1 subunit theta-like 2

1

2

High-throughput

0.536

High

1404440

CDC5L
Cell division cycle 5-like protein

1

2

High-throughput

0.536

High

1420231

UBXN6
UBX domain-containing protein 6

1

1

High-throughput

0.536

High

1433786

SENP3
Sentrin-specific protease 3

1

1

High-throughput

0.536

High

1437176

CHODL
Chondrolectin

1

5

High-throughput

0.536

High

1449719

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

1

High-throughput

0.536

High

1449722

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

4

High-throughput

0.536

High

1316594

PELP1
Proline-, glutamic acid- and leucine-rich protein 1

1

11

Small-scale

0.534

High

262321

SCN2B
Sodium channel regulatory subunit beta-2

2

3

High-throughput

0.521

High

486629

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

847795

SSRB
Translocon-associated protein subunit beta

1

0

High-throughput

0.513

High

1022483

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.513

High

1252988

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.513

High

1359159

GLMP
Glycosylated lysosomal membrane protein

1

0

High-throughput

0.513

High

1449712

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.513

High

508702

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

5

High-throughput

0.501

High

951872

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

3

High-throughput

0.501

High

1371727

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

12

High-throughput

0.501

High

412681

NTRK1
High affinity nerve growth factor receptor

1

18

High-throughput

0.500

High

465666

IGF1R
Insulin-like growth factor 1 receptor

1

19

High-throughput

0.500

High

710900

EPHB2
Ephrin type-B receptor 2

1

13

High-throughput

0.500

High

1034359

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.500

High

389535

FINC
Fibronectin

1

5

High-throughput

0.489

High

688634

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

5

High-throughput

0.489

High

771245

APJ
Apelin receptor

1

4

High-throughput

0.489

High

1142192

P2RY6
P2Y purinoceptor 6

1

6

High-throughput

0.489

High

1397666

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.489

High

1449723

GPR45
Probable G-protein coupled receptor 45

1

3

High-throughput

0.489

High

520403

ANDR
Androgen receptor

1

18

Small-scale

0.481

High

125633

LEG9
Galectin-9

1

6

High-throughput

0.479

High

126825

RHOD
Rho-related GTP-binding protein RhoD

1

12

High-throughput

0.479

High

129470

MEN1
Menin

1

3

High-throughput

0.479

High

129812

CBX4
E3 SUMO-protein ligase CBX4

1

1

Small-scale

0.479

High

170379

AURKA
Aurora kinase A

1

14

High-throughput

0.479

High

174117

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

2

High-throughput

0.479

High

181662

CETN3
Centrin-3

1

4

Small-scale

0.479

High

191120

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

6

High-throughput

0.479

High

272490

OBSL1
Obscurin-like protein 1

1

7

High-throughput

0.479

High

277412

TP4A3
Protein tyrosine phosphatase type IVA 3

1

5

High-throughput

0.479

High

294399

CD123
Translation initiation factor eIF2 assembly protein

1

4

High-throughput

0.479

High

334589

ZBT7A
Zinc finger and BTB domain-containing protein 7A

1

8

Small-scale

0.479

High

340248

PCNT
Pericentrin

1

17

High-throughput

0.479

High

345118

RIGI
Antiviral innate immune response receptor RIG-I

1

8

High-throughput

0.479

High

346392

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

4

High-throughput

0.479

High

349259

LATS1
Serine/threonine-protein kinase LATS1

1

14

High-throughput

0.479

High

404465

GCR
Glucocorticoid receptor

1

18

High-throughput

0.479

High

419232

H2A1B
Histone H2A type 1-B/E

1

7

High-throughput

0.479

High

447492

NPM
Nucleophosmin

1

2

High-throughput

0.479

High

487804

PARP1
Poly [ADP-ribose] polymerase 1

1

7

High-throughput

0.479

High

589815

RFA2
Replication protein A 32 kDa subunit

1

9

High-throughput

0.479

High

591857

H2AX
Histone H2AX

1

9

High-throughput

0.479

High

599632

STMN1
Stathmin

1

1

High-throughput

0.479

High

610054

VGFR1
Vascular endothelial growth factor receptor 1

1

8

High-throughput

0.479

High

650447

FGFR3
Fibroblast growth factor receptor 3

1

20

High-throughput

0.479

High

675176

TNR6
Tumor necrosis factor receptor superfamily member 6

1

6

High-throughput

0.479

High

696633

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

714452

PML
Protein PML

1

15

High-throughput

0.479

High

720338

UFO
Tyrosine-protein kinase receptor UFO

1

17

High-throughput

0.479

High

731640

STIP1
Stress-induced-phosphoprotein 1

1

6

High-throughput

0.479

High

755005

H2B1B
Histone H2B type 1-B

1

20

High-throughput

0.479

High

766890

PHB1
Prohibitin 1

1

9

High-throughput

0.479

High

769300

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.479

High

778107

VGFR2
Vascular endothelial growth factor receptor 2

1

8

High-throughput

0.479

High

787086

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

7

High-throughput

0.479

High

799507

BRCA1
Breast cancer type 1 susceptibility protein

1

12

High-throughput

0.479

High

879513

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

5

High-throughput

0.479

High

883339

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

3

High-throughput

0.479

High

885714

CASP4
Caspase-4

1

2

High-throughput

0.479

High

909716

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

20

High-throughput

0.479

High

910219

RND2
Rho-related GTP-binding protein RhoN

1

10

High-throughput

0.479

High

935183

TERA
Transitional endoplasmic reticulum ATPase

1

6

High-throughput

0.479

High

941975

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.479

High

954747

SEM1
26S proteasome complex subunit SEM1

1

1

Small-scale

0.479

High

955657

CDC42
Cell division control protein 42 homolog

1

8

High-throughput

0.479

High

959270

ABCE1
ATP-binding cassette sub-family E member 1

1

3

High-throughput

0.479

High

962542

RHOA
Transforming protein RhoA

1

10

High-throughput

0.479

High

966929

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

971157

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

9

High-throughput

0.479

High

978342

RHOB
Rho-related GTP-binding protein RhoB

1

10

High-throughput

0.479

High

988752

RAC1
Ras-related C3 botulinum toxin substrate 1

1

8

High-throughput

0.479

High

1088223

MERTK
Tyrosine-protein kinase Mer

1

19

High-throughput

0.479

High

1088577

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

16

High-throughput

0.479

High

1089031

TP53B
TP53-binding protein 1

1

7

High-throughput

0.479

High

1096829

RFA4
Replication protein A 30 kDa subunit

1

9

High-throughput

0.479

High

1107258

BIRC3
Baculoviral IAP repeat-containing protein 3

1

5

High-throughput

0.479

High

1121091

BOP1
Ribosome biogenesis protein BOP1

1

13

Small-scale

0.479

High

1132240

CBX2
Chromobox protein homolog 2

1

1

Small-scale

0.479

High

1133003

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

16

High-throughput

0.479

High

1135127

CUL7
Cullin-7

1

6

High-throughput

0.479

High

1139687

SYK
Lysine--tRNA ligase

1

1

High-throughput

0.479

High

1141967

EEA1
Early endosome antigen 1

1

18

High-throughput

0.479

High

1177651

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

3

High-throughput

0.479

High

1178412

CL16A
Protein CLEC16A

1

3

High-throughput

0.479

High

1220837

RN123
E3 ubiquitin-protein ligase RNF123

1

13

High-throughput

0.479

High

1229707

VIR
Protein virilizer homolog

1

3

High-throughput

0.479

High

1235539

IFIX
Pyrin and HIN domain-containing protein 1

1

1

High-throughput

0.479

High

1258394

MOB3C
MOB kinase activator 3C

1

3

High-throughput

0.479

High

1276850

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.479

High

1312506

PHC2
Polyhomeotic-like protein 2

1

7

Small-scale

0.479

High

1314441

SLX4
Structure-specific endonuclease subunit SLX4

1

14

High-throughput

0.479

High

1325399

STAG2
Cohesin subunit SA-2

1

1

High-throughput

0.479

High

1338393

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

1351990

RBCC1
RB1-inducible coiled-coil protein 1

1

18

High-throughput

0.479

High

1352778

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

2

High-throughput

0.479

High

1364617

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

8

High-throughput

0.479

High

1366588

AKAP1
A-kinase anchor protein 1, mitochondrial

1

5

High-throughput

0.479

High

1367384

ESR2
Estrogen receptor beta

1

18

High-throughput

0.479

High

1369582

ATOH1
Transcription factor ATOH1

1

9

Small-scale

0.479

High

1371930

STMN2
Stathmin-2

1

1

High-throughput

0.479

High

1383106

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.479

High

1385638

DCPS
m7GpppX diphosphatase

1

2

High-throughput

0.479

High

1393739

DDRGK
DDRGK domain-containing protein 1

1

2

High-throughput

0.479

High

1397474

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.479

High

1405874

DNJC7
DnaJ homolog subfamily C member 7

1

11

High-throughput

0.479

High

1418609

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

2

High-throughput

0.479

High

1428136

WDR12
Ribosome biogenesis protein WDR12

1

15

Small-scale

0.479

High

1428643

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

1

High-throughput

0.479

High

1430597

CCDC8
Coiled-coil domain-containing protein 8

1

4

High-throughput

0.479

High

1433447

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

11

High-throughput

0.479

High

1433850

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

14

High-throughput

0.479

High

1438181

RHOF
Rho-related GTP-binding protein RhoF

1

11

High-throughput

0.479

High

1448201

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

8

High-throughput

0.479

High

1449704

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

2

High-throughput

0.479

High

1449710

TRM7
tRNA

1

4

High-throughput

0.479

High

1449711

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.479

High

1449717

SMC3
Structural maintenance of chromosomes protein 3

1

7

High-throughput

0.479

High

1449721

FBW1A
F-box/WD repeat-containing protein 1A

1

13

High-throughput

0.479

High

1401714

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

0

High-throughput

0.458

High

1417388

STK31
Serine/threonine-protein kinase 31

1

0

High-throughput

0.458

High

1431816

EPC1
Enhancer of polycomb homolog 1

1

0

High-throughput

0.458

High

1449725

SCC4
MAU2 chromatid cohesion factor homolog

1

0

High-throughput

0.458

High

1351597

MIPT3
TRAF3-interacting protein 1

1

7

High-throughput

0.457

High

171591

S27A2
Long-chain fatty acid transport protein 2

1

3

High-throughput

0.445

High

296635

TNF13
Tumor necrosis factor ligand superfamily member 13

1

1

High-throughput

0.445

High

414708

P53
Cellular tumor antigen p53

1

6

High-throughput

0.445

High

530442

TAU
Microtubule-associated protein tau

1

15

Small-scale

0.445

High

638533

FPR1
fMet-Leu-Phe receptor

1

4

High-throughput

0.445

High

765922

BMI1
Polycomb complex protein BMI-1

1

10

High-throughput

0.445

High

869522

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

1

High-throughput

0.445

High

944078

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

11

High-throughput

0.445

High

1130478

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

7

High-throughput

0.445

High

1199716

KLH22
Kelch-like protein 22

1

7

High-throughput

0.445

High

1227545

A16L1
Autophagy-related protein 16-1

1

14

High-throughput

0.445

High

1240968

S27A4
Long-chain fatty acid transport protein 4

1

3

High-throughput

0.445

High

1363460

S39A7
Zinc transporter SLC39A7

1

3

High-throughput

0.445

High

1384633

S67A1
Solute carrier family 67 member A1

1

2

High-throughput

0.445

High

1448669

GTR9
Solute carrier family 2, facilitated glucose transporter member 9

1

2

High-throughput

0.445

High

1449703

S39A9
Zinc transporter ZIP9

1

3

High-throughput

0.445

High

1449706

SCN3B
Sodium channel regulatory subunit beta-3

1

2

High-throughput

0.445

High

1449716

XCT
Cystine/glutamate transporter

1

1

High-throughput

0.445

High

1449720

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

1

High-throughput

0.445

High

106718

APRIO
Alternative prion protein

1

6

High-throughput

0.437

High

154890

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

5

High-throughput

0.437

High

353581

AGR2
Anterior gradient protein 2 homolog

1

5

High-throughput

0.437

High

450351

ACBP
Acyl-CoA-binding protein

1

1

High-throughput

0.437

High

835446

GRM5
Metabotropic glutamate receptor 5

1

2

High-throughput

0.437

High

1126187

GRM2
Metabotropic glutamate receptor 2

1

2

High-throughput

0.437

High

1151898

RHOH
Rho-related GTP-binding protein RhoH

1

10

High-throughput

0.437

High

1186148

ANR55
Ankyrin repeat domain-containing protein 55

1

12

High-throughput

0.437

High

1255741

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.437

High

1396641

RHOV
Rho-related GTP-binding protein RhoV

1

10

High-throughput

0.437

High

1410879

MGME1
Mitochondrial genome maintenance exonuclease 1

1

1

High-throughput

0.437

High

1419423

RHBT2
Rho-related BTB domain-containing protein 2

1

16

High-throughput

0.437

High

1433531

RHOJ
Rho-related GTP-binding protein RhoJ

1

10

High-throughput

0.437

High

1434010

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

1439411

E41LA
Band 4.1-like protein 4A

1

7

High-throughput

0.437

High

1449715

HECD1
E3 ubiquitin-protein ligase HECTD1

1

6

High-throughput

0.437

High

380164

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.426

High

1181438

P3H1
Prolyl 3-hydroxylase 1

1

0

High-throughput

0.426

High

1292416

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

0

High-throughput

0.426

High

1434830

STN1
CST complex subunit STN1

1

0

High-throughput

0.426

High

1138

SIM26
Small integral membrane protein 26

1

1

High-throughput

0.407

High

619935

VCAM1
Vascular cell adhesion protein 1

1

6

High-throughput

0.407

High

683348

TNR5
Tumor necrosis factor receptor superfamily member 5

1

6

High-throughput

0.407

High

914489

EFNB2
Ephrin-B2

1

1

High-throughput

0.407

High

946643

S26A5
Prestin

1

2

High-throughput

0.407

High

1219552

ANR22
Ankyrin repeat domain-containing protein 22

1

7

High-throughput

0.407

High

1335745

MOT11
Monocarboxylate transporter 11

1

1

High-throughput

0.407

High

1412074

S39A3
Zinc transporter ZIP3

1

3

High-throughput

0.407

High

1420327

CD244
Natural killer cell receptor 2B4

1

2

High-throughput

0.407

High

1421360

S39A8
Metal cation symporter ZIP8

1

3

High-throughput

0.407

High

1446709

TMM9B
Transmembrane protein 9B

1

1

High-throughput

0.407

High

1449714

TTC7A
Tetratricopeptide repeat protein 7A

1

8

Small-scale

0.407

High

749284

CD70
CD70 antigen

2

0

High-throughput

0.328

High

1399627

OPALI
Opalin

2

0

High-throughput

0.313

High

1430885

METL9
Protein-L-histidine N-pros-methyltransferase

2

0

High-throughput

0.313

High

1430977

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

1449709

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

1108517

NAR3
Ecto-ADP-ribosyltransferase 3

1

0

High-throughput

0.249

Low

1449707

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

0

High-throughput

0.249

Low

1449718

LAMP3
Lysosome-associated membrane glycoprotein 3

1

0

High-throughput

0.249

Low

166428

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

0

High-throughput

0.232

Low

190497

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.232

Low

1185905

TMM95
Sperm-egg fusion protein TMEM95

1

0

High-throughput

0.232

Low

1449275

S22AB
Solute carrier family 22 member 11

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025