Interactor 1: CYH3 (O43739)
Cytohesin-3 (ARF nucleotide-binding site opener 3) (Protein ARNO3) (General receptor of phosphoinositides 1) (Grp1) (PH, SEC7 and coiled-coil domain-containing protein 3)
Gene: CYTH3

Interactor 2: ITSN1 (Q15811)
Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)
Gene: ITSN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 35914814
Identification Methods two hybrid, two hybrid fragment pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~RhoGEF, PH~SH3_1, PH~SH3_9
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 400
Hs

1 1721
+ Hs
+ Hs
+ Mm
+ Mm
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Last updated: 15 Jul 2024