HitPredict

Interactor 1: SGTA (O43765)
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Alpha-SGT) (Vpu-binding protein) (UBP)
Gene: SGTA

Interactor 2: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	24753260, 12482202
Identification Methods	pull down, far western blotting
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HSP90~TPR_8
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 313 Hs			1 732
+	Hs
		213454 SGTA_HUMAN (1-313): 1.79e-68: 217: 100.00		HS90B_HUMAN (19-732): 0: 1059: 86.13
+	Hs
		111935 PPP5_HUMAN (66-233): 3.75e-40: 148: 28.57		K9JA46_HUMAN (1-732): 0: 1087: 100.00
+	Hs
		431681 PPP5_HUMAN (66-233): 3.75e-40: 148: 28.57		HS90A_HUMAN (1-732): 0: 1087: 100.00
+	Hs
		432363 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		HS90A_HUMAN (1-732): 0: 1087: 100.00
+	Mm
		432427 PPP5_MOUSE (66-233): 8.06e-41: 150: 28.57		HS90A_MOUSE (1-732): 0: 1083: 97.82
+	Mm
		513680 PPP5_MOUSE (66-233): 8.06e-41: 150: 28.57		HS90B_MOUSE (19-732): 0: 1063: 86.98
+	Hs
		438021 PPP5_HUMAN (66-233): 3.75e-40: 148: 28.57		HS90B_HUMAN (19-732): 0: 1059: 86.13
+	Hs
		438621 CHIP_HUMAN (66-229): 1.29e-41: 148: 27.22		HS90B_HUMAN (19-732): 0: 1059: 86.13
+	Dm
		365470 Q9V3E9_DROME (3-239): 1.24e-38: 144: 22.63		HSP83_DROME (15-732): 0: 1034: 78.41
+	At
		99224 OE64M_ARATH (58-206): 1.1e-40: 151: 35.57		HS904_ARATH (15-732): 0: 987: 68.24
+	At
		137805 OE64C_ARATH (45-204): 1.8e-39: 147: 30.00		HS904_ARATH (15-732): 0: 987: 68.24
+	At
		99228 OE64M_ARATH (58-206): 1.1e-40: 151: 35.57		HS902_ARATH (15-732): 0: 982: 68.24
+	At
		99226 OE64M_ARATH (58-206): 1.1e-40: 151: 35.57		HS901_ARATH (15-732): 0: 981: 69.49
+	At
		878283 OE64C_ARATH (45-204): 1.8e-39: 147: 30.00		HS902_ARATH (15-732): 0: 982: 68.24
+	At
		646594 OE64C_ARATH (45-204): 1.8e-39: 147: 30.00		HS901_ARATH (15-732): 0: 981: 69.49
+	Hs
		538353 SGTB_HUMAN (1-311): 5.27e-54: 180: 57.24		ENPL_HUMAN (14-701): 0: 898: 46.78
+	Mm
		435924 PPP5_MOUSE (66-233): 8.06e-41: 150: 28.57		ENPL_MOUSE (14-732): 0: 901: 45.07
+	Zm
		33277 A0A1D6L1L3_MAIZE (45-195): 5.71e-41: 152: 33.78		A0A1D6LMW9_MAIZE (4-704): 0: 843: 46.30
+	Hs
		858632 PPP5_HUMAN (66-233): 3.75e-40: 148: 28.57		H90B4_HUMAN (30-604): 0: 571: 62.61
+	Dm
		1358467 Q9V3E9_DROME (3-239): 1.24e-38: 144: 22.63		Q9VAY2_DROME (15-700): 0: 537: 46.13