HitPredict

Interactor 1: MYO1B (O43795)
Unconventional myosin-Ib (MYH-1c) (Myosin I alpha) (MMI-alpha) (MMIa)
Gene: MYO1B

Interactor 2: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005516 - calmodulin binding GO:0005886 - plasma membrane GO:0015629 - actin cytoskeleton GO:0045296 - cadherin binding GO:0051017 - actin filament bundle assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1136 Hs			1 793
+	Hs
		214633 MYO1B_HUMAN (1-1136): 0: 1188: 100.00		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		214519 MYO1B_HUMAN (1-1136): 0: 1188: 100.00		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		148174 MYO1B_HUMAN (1-1136): 0: 1188: 100.00		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		214675 MYO1B_HUMAN (1-1136): 0: 1188: 100.00		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38
+	Hs
		1268124 MYO5A_HUMAN (2-1125): 0: 1013: 28.64		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Dm
		1303383 MYO7A_DROME (3-914): 0: 1014: 33.70		MYSN_DROME (2-660): 2.34e-25: 115: 10.46
+	Hs
		1268114 MYO5B_HUMAN (7-1125): 0: 995: 28.67		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		725086 MYO5A_HUMAN (2-1125): 0: 1013: 28.64		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		725065 MYO5B_HUMAN (7-1125): 0: 995: 28.67		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		1343920 MYO5A_HUMAN (2-1125): 0: 1013: 28.64		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38
+	Ce
		136791 HUM6_CAEEL (16-808): 0: 963: 35.26		UNC89_CAEEL (214-792): 7.29e-12: 71.7: 14.36
+	Hs
		1021686 MYO1E_HUMAN (16-729): 0: 622: 46.27		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		724801 MYO1E_HUMAN (16-729): 0: 622: 46.27		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		148746 MYO1E_HUMAN (16-729): 0: 622: 46.27		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		1021711 MYO1E_HUMAN (16-729): 0: 622: 46.27		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38
+	Hs
		117671 MYO1C_HUMAN (778-1136): 9.49e-71: 259: 25.95		CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00
+	Hs
		117781 MYO1C_HUMAN (778-1136): 9.49e-71: 259: 25.95		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		117872 MYO1C_HUMAN (778-1136): 9.49e-71: 259: 25.95		MYO5A_HUMAN (42-632): 2.15e-24: 112: 15.29
+	Hs
		117614 MYO1C_HUMAN (778-1136): 9.49e-71: 259: 25.95		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		117506 MYO1C_HUMAN (778-1136): 9.49e-71: 259: 25.95		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87