Protein: WDR3
WD repeat-containing protein 3

Gene: WDR3
Organism: Homo sapiens
Interactions: 154
UniProt ID: Q9UNX4

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0030490 - maturation of SSU-rRNA
GO:0030515 - snoRNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1085730

TBL3
Transducin beta-like protein 3

2

17

High-throughput

0.789

High

1144753

PWP2
Periodic tryptophan protein 2 homolog

1

19

High-throughput

0.691

High

1341169

WDR36
WD repeat-containing protein 36

1

20

High-throughput

0.691

High

447586

NPM
Nucleophosmin

3

10

High-throughput

0.667

High

373500

MYC
Myc proto-oncogene protein

3

20

High-throughput

0.640

High

208427

RRP8
Ribosomal RNA-processing protein 8

2

4

High-throughput

0.628

High

1416147

RBM4
RNA-binding protein 4

2

18

High-throughput

0.628

High

141168

NOP56
Nucleolar protein 56

2

12

High-throughput

0.611

High

1454361

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

2

11

High-throughput

0.611

High

1405176

MPH6
M-phase phosphoprotein 6

2

3

High-throughput

0.601

High

1447240

EXOS5
Exosome complex component RRP46

2

20

High-throughput

0.601

High

129557

MEN1
Menin

2

4

High-throughput

0.584

High

590035

RFA2
Replication protein A 32 kDa subunit

2

7

High-throughput

0.584

High

644131

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

11

High-throughput

0.584

High

696866

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

6

High-throughput

0.584

High

769516

RFA3
Replication protein A 14 kDa subunit

2

8

High-throughput

0.584

High

979352

RS6
Small ribosomal subunit protein eS6

2

6

High-throughput

0.584

High

935472

FGF8
Fibroblast growth factor 8

2

3

High-throughput

0.574

High

1398102

ZN512
Zinc finger protein 512

2

1

High-throughput

0.574

High

1436018

PACC1
Proton-activated chloride channel

2

1

High-throughput

0.574

High

397223

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

162738

ANM5
Protein arginine N-methyltransferase 5

1

7

High-throughput

0.536

High

290796

SURF6
Surfeit locus protein 6

1

3

High-throughput

0.536

High

339010

CBX6
Chromobox protein homolog 6

1

9

High-throughput

0.536

High

445620

IF4E
Eukaryotic translation initiation factor 4E

1

3

High-throughput

0.536

High

612016

RL35A
Large ribosomal subunit protein eL33

1

4

High-throughput

0.536

High

833223

MNDA
Myeloid cell nuclear differentiation antigen

1

13

High-throughput

0.536

High

854387

KI67
Proliferation marker protein Ki-67

1

5

High-throughput

0.536

High

859115

RL27A
Large ribosomal subunit protein uL15

1

5

High-throughput

0.536

High

872891

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.536

High

970173

RS16
Small ribosomal subunit protein uS9

1

10

High-throughput

0.536

High

1027850

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

14

High-throughput

0.536

High

1089927

ILF3
Interleukin enhancer-binding factor 3

1

16

High-throughput

0.536

High

1101100

G3BP1
Ras GTPase-activating protein-binding protein 1

1

5

High-throughput

0.536

High

1258274

UBP43
Ubiquitin carboxyl-terminal hydrolase 43

1

14

High-throughput

0.536

High

1272595

CSN6
COP9 signalosome complex subunit 6

1

3

High-throughput

0.536

High

1360529

PSPC1
Paraspeckle component 1

1

20

High-throughput

0.536

High

1409876

RBM4B
RNA-binding protein 4B

1

18

High-throughput

0.536

High

1410407

MEP50
Methylosome protein WDR77

1

16

High-throughput

0.536

High

1446207

EXOS4
Exosome complex component RRP41

1

20

High-throughput

0.536

High

1446897

TF7L2
Transcription factor 7-like 2

1

20

High-throughput

0.536

High

785533

RL4
Large ribosomal subunit protein uL4

1

8

High-throughput

0.515

High

926244

ICLN
Methylosome subunit pICln

1

0

High-throughput

0.513

High

876742

HSP13
Heat shock 70 kDa protein 13

1

16

High-throughput

0.494

High

539021

EPB41
Protein 4.1

1

2

High-throughput

0.489

High

657330

KALM
Anosmin-1

1

3

High-throughput

0.489

High

1038487

TIE2
Angiopoietin-1 receptor

1

3

High-throughput

0.489

High

1163622

RTN1
Reticulon-1

1

2

High-throughput

0.489

High

1247568

TSSK4
Testis-specific serine/threonine-protein kinase 4

1

4

High-throughput

0.489

High

1281496

ZN467
Zinc finger protein 467

1

1

High-throughput

0.489

High

1313605

DDX60
Probable ATP-dependent RNA helicase DDX60

1

16

High-throughput

0.489

High

1399817

TECTB
Beta-tectorin

1

4

High-throughput

0.489

High

1462410

ANR26
Ankyrin repeat domain-containing protein 26

1

17

High-throughput

0.489

High

1462413

KLH20
Kelch-like protein 20

1

5

High-throughput

0.489

High

343657

OXSR1
Serine/threonine-protein kinase OSR1

1

6

Small-scale

0.481

High

1462414

NOP58
Nucleolar protein 58

1

12

High-throughput

0.481

High

191160

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

2

High-throughput

0.479

High

223426

PRC1
Protein regulator of cytokinesis 1

1

11

High-throughput

0.479

High

248142

NUPR1
Nuclear protein 1

1

4

High-throughput

0.479

High

260614

BRD4
Bromodomain-containing protein 4

1

14

High-throughput

0.479

High

274808

DNJB6
DnaJ homolog subfamily B member 6

1

14

High-throughput

0.479

High

285524

EED
Polycomb protein EED

1

18

High-throughput

0.479

High

298462

DNJC8
DnaJ homolog subfamily C member 8

1

13

High-throughput

0.479

High

331421

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

346502

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

16

High-throughput

0.479

High

406801

MYCN
N-myc proto-oncogene protein

1

20

High-throughput

0.479

High

409132

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

2

High-throughput

0.479

High

414856

P53
Cellular tumor antigen p53

1

9

High-throughput

0.479

High

474374

NFIC
Nuclear factor 1 C-type

1

11

High-throughput

0.479

High

487886

PARP1
Poly [ADP-ribose] polymerase 1

1

7

High-throughput

0.479

High

731703

STIP1
Stress-induced-phosphoprotein 1

1

16

High-throughput

0.479

High

773083

MYH9
Myosin-9

1

8

High-throughput

0.479

High

831651

CCNF
Cyclin-F

1

6

High-throughput

0.479

High

851704

GATA4
Transcription factor GATA-4

1

7

Small-scale

0.479

High

879616

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

8

High-throughput

0.479

High

883367

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

10

High-throughput

0.479

High

920366

PLK1
Serine/threonine-protein kinase PLK1

1

9

High-throughput

0.479

High

980544

H4
Histone H4

1

6

High-throughput

0.479

High

982877

RS24
Small ribosomal subunit protein eS24

1

4

High-throughput

0.479

High

985070

RL31
Large ribosomal subunit protein eL31

1

3

High-throughput

0.479

High

1005249

RNF4
E3 ubiquitin-protein ligase RNF4

1

5

High-throughput

0.479

High

1008939

RED1
Double-stranded RNA-specific editase 1

1

12

High-throughput

0.479

High

1032266

EXOSX
Exosome complex component 10

1

8

High-throughput

0.479

High

1035995

KIF23
Kinesin-like protein KIF23

1

14

High-throughput

0.479

High

1087618

GRSF1
G-rich sequence factor 1

1

20

High-throughput

0.479

High

1088619

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

15

High-throughput

0.479

High

1097631

CBX3
Chromobox protein homolog 3

1

8

High-throughput

0.479

High

1107337

BIRC3
Baculoviral IAP repeat-containing protein 3

1

10

High-throughput

0.479

High

1133049

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

15

High-throughput

0.479

High

1138172

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

1155134

USF2
Upstream stimulatory factor 2

1

20

Small-scale

0.479

High

1161760

IF16
Gamma-interferon-inducible protein 16

1

13

High-throughput

0.479

High

1206804

RRP12
RRP12-like protein

1

4

High-throughput

0.479

High

1238508

ZN746
Zinc finger protein 746

1

4

High-throughput

0.479

High

1290820

ZCH18
Zinc finger CCCH domain-containing protein 18

1

16

High-throughput

0.479

High

1313532

SMC5
Structural maintenance of chromosomes protein 5

1

3

High-throughput

0.479

High

1326381

NIN
Ninein

1

20

High-throughput

0.479

High

1329947

SIR6
NAD-dependent protein deacylase sirtuin-6

1

10

High-throughput

0.479

High

1339038

NUP43
Nucleoporin Nup43

1

17

High-throughput

0.479

High

1346990

SNIP1
Smad nuclear-interacting protein 1

1

1

High-throughput

0.479

High

1352837

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.479

High

1361261

DNJC9
DnaJ homolog subfamily C member 9

1

20

High-throughput

0.479

High

1367595

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1380688

FBX32
F-box only protein 32

1

1

High-throughput

0.479

High

1384906

CHCH1
Small ribosomal subunit protein mS37

1

3

High-throughput

0.479

High

1387644

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

18

High-throughput

0.479

High

1393826

DDRGK
DDRGK domain-containing protein 1

1

5

High-throughput

0.479

High

1397561

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.479

High

1418642

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

13

High-throughput

0.479

High

1428673

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

2

High-throughput

0.479

High

1429821

XRN2
5'-3' exoribonuclease 2

1

4

High-throughput

0.479

High

1438082

RC3H2
Roquin-2

1

11

High-throughput

0.479

High

1447444

ANLN
Anillin

1

6

High-throughput

0.479

High

1448243

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

10

High-throughput

0.479

High

1450697

DJC17
DnaJ homolog subfamily C member 17

1

20

High-throughput

0.479

High

1453050

TLS1
Splicing factor C9orf78

1

5

High-throughput

0.479

High

1461307

NUP50
Nuclear pore complex protein Nup50

1

4

High-throughput

0.479

High

1462395

RL26L
Ribosomal protein uL24-like

1

5

High-throughput

0.479

High

1462411

CE164
Centrosomal protein of 164 kDa

1

20

High-throughput

0.479

High

1323187

CCAR2
Cell cycle and apoptosis regulator protein 2

1

0

High-throughput

0.460

High

800171

COIL
Coilin

1

0

High-throughput

0.458

High

1453550

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.458

High

288819

NPM3
Nucleoplasmin-3

1

10

High-throughput

0.445

High

430511

JUN
Transcription factor Jun

1

14

High-throughput

0.445

High

601906

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.445

High

1006797

SRPK2
SRSF protein kinase 2

1

18

High-throughput

0.445

High

1119082

C1D
Nuclear nucleic acid-binding protein C1D

1

2

High-throughput

0.445

High

1130529

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

8

High-throughput

0.445

High

1239980

CAVN1
Caveolae-associated protein 1

1

4

High-throughput

0.445

High

1453467

NOP53
Ribosome biogenesis protein NOP53

1

4

High-throughput

0.445

High

66909

SPDE4
Speedy protein E4

1

1

High-throughput

0.437

High

67108

ENO4
Enolase 4

1

3

High-throughput

0.437

High

157993

CTRO
Citron Rho-interacting kinase

1

10

High-throughput

0.437

High

243297

PRKN
E3 ubiquitin-protein ligase parkin

1

14

High-throughput

0.437

High

272550

OBSL1
Obscurin-like protein 1

1

7

High-throughput

0.437

High

401704

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.437

High

773306

MYH10
Myosin-10

1

8

High-throughput

0.437

High

776869

MYH11
Myosin-11

1

8

High-throughput

0.437

High

941858

ARL4C
ADP-ribosylation factor-like protein 4C

1

7

High-throughput

0.437

High

971292

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

11

High-throughput

0.437

High

1135178

CUL7
Cullin-7

1

5

High-throughput

0.437

High

1141043

KIF14
Kinesin-like protein KIF14

1

10

High-throughput

0.437

High

1256104

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.437

High

1352555

GPX8
Probable glutathione peroxidase 8

1

1

High-throughput

0.437

High

1385920

CHM4C
Charged multivesicular body protein 4c

1

9

High-throughput

0.437

High

1418523

ACE2
Angiotensin-converting enzyme 2

1

2

High-throughput

0.437

High

1428423

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

4

High-throughput

0.437

High

1433127

CHM4B
Charged multivesicular body protein 4b

1

9

High-throughput

0.437

High

1434236

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

1461695

HECD1
E3 ubiquitin-protein ligase HECTD1

1

19

High-throughput

0.437

High

1462412

PDE10
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

1

4

High-throughput

0.417

High

1307858

TPPC5
Trafficking protein particle complex subunit 5

1

0

High-throughput

0.249

Low

62612

S35F4
Solute carrier family 35 member F4

1

0

High-throughput

0.232

Low

1461545

S39AA
Zinc transporter ZIP10

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025