Interactor 1: CPSF5 (O43809)
Cleavage and polyadenylation specificity factor subunit 5 (Cleavage and polyadenylation specificity factor 25 kDa subunit) (CPSF 25 kDa subunit) (Cleavage factor Im complex 25 kDa subunit) (CFIm25) (Nucleoside diphosphate-linked moiety X motif 21) (Nudix motif 21) (Nudix hydrolase 21) (Pre-mRNA cleavage factor Im 68 kDa subunit)
Gene: NUDT21

Interactor 2: SIR2 (Q8IXJ6)
NAD-dependent protein deacetylase sirtuin-2 (EC 2.3.1.286) (NAD-dependent protein defatty-acylase sirtuin-2) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 2) (SIR2-like protein 2)
Gene: SIRT2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 17172643
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0042826 - histone deacetylase binding
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 227
Hs

1 389
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024