Interactor 1: ORC5 (O43913)
Origin recognition complex subunit 5
Gene: ORC5
Interactor 2: ORC4 (O43929)
Origin recognition complex subunit 4
Gene: ORC4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.90 | 1.00 | 0.953 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12614612, 9765232, 36652389, 26264872, 11395502, 15232106, 17716973 |
| Identification Methods | two hybrid, affinity chromatography technology, cross-linking study, biochemical, pull down, protein array, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AAA_16~AAA_16, AAA_16~ORC4_C, AAA_16~ORC5_C, ORC4_C~ORC5_C |
| Common GO terms | GO:0000166 - nucleotide binding GO:0000781 - chromosome, telomeric region GO:0000808 - origin recognition complex GO:0003688 - DNA replication origin binding GO:0005524 - ATP binding and 5 others more... |
| Homologous interactions | 19 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
