HitPredict

Interactor 1: ORC5 (O43913)
Origin recognition complex subunit 5
Gene: ORC5

Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.563

Property	Details
Experiments	20850016, 30804502
Identification Methods	unspecified method, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 435 Hs			1 103
+	Hs
		917812 CDC6_HUMAN (2-318): 3.42e-89: 283: 13.37		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917216 ORC1_HUMAN (1-307): 9.45e-80: 265: 12.42		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Sc
		356596 ORC5_YEAST (6-433): 1.29e-86: 273: 21.52		H4_YEAST (18-103): 6.13e-41: 132: 90.70
+	At
		287544 CDC6A_ARATH (1-322): 1.72e-64: 218: 14.13		H4_ARATH (1-103): 3.47e-48: 150: 98.06
+	Sc
		356645 ORC1_YEAST (8-238): 7.5e-51: 186: 12.37		H4_YEAST (18-103): 6.13e-41: 132: 90.70
+	Hs
		217791 ORC4_HUMAN (6-286): 1.48e-36: 140: 14.65		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		721961 RFC4_HUMAN (3-235): 6.17e-09: 59.4: 12.71		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Sc
		356648 ORC4_YEAST (12-181): 3.13e-09: 60.9: 16.92		H4_YEAST (18-103): 6.13e-41: 132: 90.70