Protein: HELZ
Probable helicase with zinc finger domain (EC 3.6.4.-) (Down-regulated in human cancers protein)

Gene: HELZ
Organism: Homo sapiens
Interactions: 76
UniProt ID: P42694

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0004386 - helicase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

789140

RACK1
Small ribosomal subunit protein RACK1

3

5

High-throughput

0.817

High

198853

RFOX2
RNA binding protein fox-1 homolog 2

2

12

High-throughput

0.712

High

47752

RBM47
RNA-binding protein 47

1

10

High-throughput

0.575

High

789143

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

20

High-throughput

0.575

High

789165

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

13

High-throughput

0.575

High

789169

PABP5
Polyadenylate-binding protein 5

1

9

High-throughput

0.575

High

789177

RBM4B
RNA-binding protein 4B

1

15

High-throughput

0.575

High

789178

TCAB1
Telomerase Cajal body protein 1

1

6

High-throughput

0.575

High

789179

LST8
Target of rapamycin complex subunit LST8

1

4

High-throughput

0.575

High

789187

TSAP1
tRNA selenocysteine 1-associated protein 1

1

12

High-throughput

0.575

High

789152

ESRP1
Epithelial splicing regulatory protein 1

2

16

High-throughput

0.552

High

789183

NXF2
Nuclear RNA export factor 2

2

4

High-throughput

0.552

High

789192

CELA1
Chymotrypsin-like elastase family member 1

2

1

High-throughput

0.552

High

789193

KLH20
Kelch-like protein 20

2

1

High-throughput

0.552

High

789196

HCFC2
Host cell factor 2

2

2

High-throughput

0.552

High

789157

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

Small-scale

0.549

High

789142

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.546

High

789137

BCAT1
Branched-chain-amino-acid aminotransferase, cytosolic

2

0

High-throughput

0.528

High

789167

PIGT
GPI transamidase component PIG-T

2

0

High-throughput

0.528

High

789174

WDR90
WD repeat-containing protein 90

1

4

High-throughput

0.514

High

447613

CEL3A
Chymotrypsin-like elastase family member 3A

2

1

High-throughput

0.504

High

789153

THSD4
Thrombospondin type-1 domain-containing protein 4

2

1

High-throughput

0.504

High

789159

CLASR
CLK4-associating serine/arginine rich protein

2

2

High-throughput

0.504

High

789139

GRB2
Growth factor receptor-bound protein 2

1

1

High-throughput

0.457

High

70123

B2CML4
Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3DE

1

10

High-throughput

0.445

High

164811

SC16A
Protein transport protein Sec16A

1

3

High-throughput

0.445

High

181169

NUP42
Nucleoporin NUP42

1

2

High-throughput

0.445

High

369139

ESR1
Estrogen receptor

1

11

High-throughput

0.445

High

789138

SUMO3
Small ubiquitin-related modifier 3

1

3

Small-scale

0.445

High

789144

IF16
Gamma-interferon-inducible protein 16

1

10

High-throughput

0.445

High

789145

NSN5B
Putative NOL1/NOP2/Sun domain family member 5B

1

2

High-throughput

0.445

High

789149

PKHA7
Pleckstrin homology domain-containing family A member 7

1

11

High-throughput

0.445

High

789151

SWAP1
ATPase SWSAP1

1

1

High-throughput

0.445

High

789154

NBEL2
Neurobeachin-like protein 2

1

7

High-throughput

0.445

High

789166

AKAP1
A-kinase anchor protein 1, mitochondrial

1

2

High-throughput

0.445

High

789168

EFMT3
EEF1A lysine methyltransferase 3

1

4

High-throughput

0.445

High

789171

NEIL1
Endonuclease 8-like 1

1

2

High-throughput

0.445

High

789173

LOXL4
Lysyl oxidase homolog 4

1

2

High-throughput

0.445

High

789175

TCPQM
T-complex protein 1 subunit theta-like 2

1

1

High-throughput

0.445

High

789180

DUS16
Dual specificity protein phosphatase 16

1

3

High-throughput

0.445

High

789182

UBXN6
UBX domain-containing protein 6

1

1

High-throughput

0.445

High

789185

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

2

High-throughput

0.445

High

789186

LN28A
Protein lin-28 homolog A

1

8

High-throughput

0.445

High

789190

PURG
Purine-rich element-binding protein gamma

1

3

High-throughput

0.445

High

245668

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.426

High

272338

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.426

High

277289

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.426

High

335245

DYR
Dihydrofolate reductase

1

0

High-throughput

0.426

High

532072

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.426

High

789141

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.426

High

789146

KR197
Keratin-associated protein 19-7

1

0

High-throughput

0.426

High

789147

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.426

High

789148

CBPC6
Cytosolic carboxypeptidase 6

1

0

High-throughput

0.426

High

789172

TRM61
tRNA

1

0

High-throughput

0.426

High

789176

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.426

High

789184

SHRPN
Sharpin

1

0

High-throughput

0.426

High

789189

AAKG3
5'-AMP-activated protein kinase subunit gamma-3

1

0

High-throughput

0.426

High

789191

HSPB8
Heat shock protein beta-8

1

0

High-throughput

0.426

High

789194

CDIN1
CDAN1-interacting nuclease 1

1

0

High-throughput

0.426

High

789195

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.426

High

215841

ANGL7
Angiopoietin-related protein 7

1

1

High-throughput

0.407

High

604221

TENX
Tenascin-X

1

5

High-throughput

0.407

High

645959

CRBB3
Beta-crystallin B3

1

1

High-throughput

0.407

High

789150

KLH10
Kelch-like protein 10

1

1

High-throughput

0.407

High

789155

PKHG7
Pleckstrin homology domain-containing family G member 7

1

2

High-throughput

0.407

High

789158

CRBG2
Beta/gamma crystallin domain-containing protein 2

1

3

High-throughput

0.407

High

789162

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

2

High-throughput

0.407

High

789188

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

4

High-throughput

0.407

High

341422

FA12
Coagulation factor XII

1

0

High-throughput

0.232

Low

789156

S2548
Solute carrier family 25 member 48

1

0

High-throughput

0.232

Low

789160

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

789161

IT70B
Intraflagellar transport protein 70B

1

0

High-throughput

0.232

Low

789163

CI163
Uncharacterized protein C9orf163

1

0

High-throughput

0.232

Low

789164

LY65B
Lymphocyte antigen 6 complex locus protein G5b

1

0

High-throughput

0.232

Low

789170

T3HPD
Trans-3-hydroxy-L-proline dehydratase

1

0

High-throughput

0.232

Low

789181

CHIA
Acidic mammalian chitinase

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024