HitPredict

Interactor 1: AIRE (O43918)
Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein)
Gene: AIRE

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23443559
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 545 Hs			1 2752
+	Hs
		1059945 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		1285335 PF21A_HUMAN (130-352): 7.15e-33: 135: 23.38		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		1059807 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		331745 NSD2_HUMAN (30-345): 3.09e-17: 87.5: 14.80		MAP1B_HUMAN (15-1517): 8.71e-69: 261: 10.13
+	Hs
		164388 TRI66_HUMAN (400-540): 1.72e-19: 94.8: 20.41		PRC2B_HUMAN (640-2750): 5.74e-64: 245: 9.36
+	Hs
		1300602 PHF12_HUMAN (295-340): 4.7e-09: 61.2: 54.17		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		1059815 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		MINT_HUMAN (709-2695): 5.55e-37: 157: 9.30
+	Hs
		617319 SP100_HUMAN (3-296): 1.81e-36: 146: 13.81		NIPBL_HUMAN (333-1474): 1.68e-16: 89.1: 14.39
+	Hs
		1059764 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		152679 PF21A_HUMAN (130-352): 7.15e-33: 135: 23.38		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75
+	Hs
		1059966 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		PRC2C_HUMAN (1360-2752): 9.55e-11: 70.1: 9.11
+	Hs
		1018774 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		PRC2C_HUMAN (1360-2752): 9.55e-11: 70.1: 9.11
+	Hs
		1299581 UHRF2_HUMAN (287-410): 6.73e-27: 117: 24.22		DIDO1_HUMAN (13-1216): 9.01e-11: 70.1: 10.22