Interactor 1: MED7 (O43513)
Mediator of RNA polymerase II transcription subunit 7 (hMED7) (Activator-recruited cofactor 34 kDa component) (ARC34) (Cofactor required for Sp1 transcriptional activation subunit 9) (CRSP complex subunit 9) (Mediator complex subunit 7) (RNA polymerase transcriptional regulation mediator subunit 7 homolog) (Transcriptional coactivator CRSP33)
Gene: MED7
Interactor 2: MED31 (Q9Y3C7)
Mediator of RNA polymerase II transcription subunit 31 (Mediator complex subunit 31) (Mediator complex subunit SOH1) (hSOH1)
Gene: MED31
Species: Homo sapiens
Source: mint
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.969 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35271311, 26186194, 28514442, 24981860, 33961781, 31839598, 20211142 |
| Identification Methods | affinity chromatography technology, cross-linking study, two hybrid, anti tag coimmunoprecipitation, tandem affinity purification, two hybrid array |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Med31~Med7 |
| Common GO terms | GO:0000151 - ubiquitin ligase complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0016567 - protein ubiquitination and 6 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
