HitPredict

Interactor 1: NH111 (O45521)
Nuclear hormone receptor family member nhr-111
Gene: nhr-111

Interactor 2: CES2 (Q94126)
Transcription factor ces-2 (Cell death specification protein 2)
Gene: ces-2

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 311 Ce			1 211
+	Mm
		914682 ERR3_MOUSE (4-307): 3.59e-80: 252: 20.56		HLF_MOUSE (19-181): 2.88e-26: 104: 33.13
+	Hs
		500353 RARB_HUMAN (7-304): 1.54e-80: 253: 18.26		CEBPB_HUMAN (83-188): 4.58e-24: 99.2: 23.59
+	Hs
		1055256 HNF4G_HUMAN (41-307): 3.15e-78: 245: 23.86		HLF_HUMAN (19-181): 1.16e-26: 105: 33.13
+	Hs
		369190 ESR1_HUMAN (24-307): 1.21e-75: 244: 18.16		CEBPD_HUMAN (97-183): 6.32e-25: 99.9: 26.44
+	Ce
		220176 NH111_CAEEL (1-311): 5.34e-91: 275: 100.00		Q9NAE4_CAEEL (108-177): 7.2e-14: 68.7: 41.43
+	Hs
		368942 ESR1_HUMAN (24-307): 1.21e-75: 244: 18.16		CEBPB_HUMAN (83-188): 4.58e-24: 99.2: 23.59
+	Hs
		500359 RARB_HUMAN (7-304): 1.54e-80: 253: 18.26		CEBPA_HUMAN (78-187): 2.38e-20: 89.2: 21.82
+	Hs
		368813 ESR1_HUMAN (24-307): 1.21e-75: 244: 18.16		JUN_HUMAN (3-182): 2.96e-22: 94.2: 16.43
+	Hs
		401306 NR2F6_HUMAN (8-305): 7.13e-78: 244: 20.95		JUN_HUMAN (3-182): 2.96e-22: 94.2: 16.43
+	Hs
		973610 ESR2_HUMAN (28-307): 3.92e-68: 223: 19.55		CREB5_HUMAN (75-195): 6.19e-28: 111: 23.14
+	Hs
		369189 ESR1_HUMAN (24-307): 1.21e-75: 244: 18.16		CEBPA_HUMAN (78-187): 2.38e-20: 89.2: 21.82
+	Hs
		377075 GCR_HUMAN (1-307): 2.34e-70: 234: 17.16		CEBPB_HUMAN (83-188): 4.58e-24: 99.2: 23.59
+	Mm
		450551 ERR2_MOUSE (35-307): 4.02e-71: 228: 20.00		JUNB_MOUSE (3-182): 2.91e-25: 102: 16.33
+	Hs
		377003 GCR_HUMAN (1-307): 2.34e-70: 234: 17.16		JUN_HUMAN (3-182): 2.96e-22: 94.2: 16.43
+	Hs
		487924 RARA_HUMAN (3-304): 2.36e-75: 239: 18.28		CEBPA_HUMAN (78-187): 2.38e-20: 89.2: 21.82
+	Hs
		377076 GCR_HUMAN (1-307): 2.34e-70: 234: 17.16		ATF3_HUMAN (50-198): 5.73e-23: 92.7: 16.78
+	Mm
		404119 ESR1_MOUSE (22-307): 7.53e-73: 236: 17.79		JUN_MOUSE (3-182): 5.28e-21: 90.7: 16.11
+	Mm
		404101 GCR_MOUSE (1-307): 6.81e-71: 235: 17.25		JUN_MOUSE (3-182): 5.28e-21: 90.7: 16.11
+	Hs
		377182 GCR_HUMAN (1-307): 2.34e-70: 234: 17.16		CEBPA_HUMAN (78-187): 2.38e-20: 89.2: 21.82
+	Rn
		546260 ANDR_RAT (38-301): 1.27e-62: 214: 20.12		JUN_RAT (3-182): 3.24e-21: 91.1: 16.11