HitPredict

Interactor 1: HTH (O46339)
Homeobox protein homothorax (Homeobox protein dorsotonals)
Gene: HTH

Interactor 2: EXD (P40427)
Homeobox protein extradenticle (Dpbx)
Gene: EXD

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 21276241, 30995488, 25242320, 10215621, 10529430, 12231630, 9346235, 23637332, 31251896, 14605208, 25294943, 10704852, 17981120, unassigned4
Identification Methods protein complementation assay, two hybrid, pull down, affinity chromatography technology, electrophoretic mobility shift assay, miniaturized immunoprecipitation, experimental interaction detection, two hybrid array, bimolecular fluorescence complementation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Homeobox_KN~Homeobox_KN
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0001654 - eye development
GO:0003677 - DNA binding
and 16 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 487
Dm

1 376
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Ce
+ Mm
+ Hs
+ Mm
+ Ce
+ Ce
+ Hs
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024