HitPredict

Interactor 1: VPS45 (O49048)
Vacuolar protein sorting-associated protein 45 homolog (AtVPS45) (Protein BFA-VISUALIZED ENDOCYTIC TRAFFICKING DEFECTIVE 2)
Gene: VPS45

Interactor 2: SYP41 (O65359)
Tlg2p-like protein a (AtTLG2a) (Syntaxin-41) (AtSYP41)
Gene: SYP41

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.845

Property	Details
Experiments	10888666, 24556609
Identification Methods	affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	SNARE~Sec1
Common GO terms	GO:0005802 - trans-Golgi network GO:0006886 - intracellular protein transport GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 569 At			1 322
+	At
		221476 VPS45_ARATH (1-569): 0: 604: 100.00		SYP43_ARATH (1-322): 1.39e-84: 260: 84.29
+	At
		221477 VPS45_ARATH (1-569): 0: 604: 100.00		SYP42_ARATH (1-322): 8.37e-78: 242: 63.61
+	Hs
		152179 VPS45_HUMAN (1-564): 4.34e-180: 521: 44.62		STX16_HUMAN (1-298): 1.9e-66: 213: 33.00
+	Mm
		192851 STXB2_MOUSE (2-560): 3.46e-175: 509: 19.90		STX1A_MOUSE (51-321): 2.12e-66: 211: 18.47
+	Rn
		699178 STXB2_RAT (2-560): 3.99e-173: 504: 20.20		STX1A_RAT (51-321): 2.9e-66: 211: 18.47
+	Hs
		699262 STXB2_HUMAN (2-560): 2.53e-172: 502: 19.39		STX2_HUMAN (51-318): 5.35e-65: 208: 17.31
+	Hs
		898829 STXB1_HUMAN (2-566): 7.31e-170: 496: 18.91		STX1B_HUMAN (51-321): 1.1e-66: 212: 18.88
+	Bt
		699167 STXB1_BOVIN (2-566): 7.31e-170: 496: 18.91		STX1A_BOVIN (51-321): 1.42e-65: 209: 18.82
+	Hs
		699253 STXB1_HUMAN (2-566): 7.31e-170: 496: 18.91		STX2_HUMAN (51-318): 5.35e-65: 208: 17.31
+	Rn
		838510 STXB2_RAT (2-560): 3.99e-173: 504: 20.20		STX2_RAT (51-300): 1.99e-57: 188: 17.23
+	Hs
		1017818 VPS45_HUMAN (1-564): 4.34e-180: 521: 44.62		STX4_HUMAN (41-318): 8.28e-49: 166: 18.90
+	Hs
		1205380 VPS45_HUMAN (1-564): 4.34e-180: 521: 44.62		STX12_HUMAN (67-305): 2.21e-46: 159: 20.40
+	Hs
		178807 VPS45_HUMAN (1-564): 4.34e-180: 521: 44.62		STX7_HUMAN (71-320): 1.48e-46: 159: 20.08
+	Mm
		1145332 STXB2_MOUSE (2-560): 3.46e-175: 509: 19.90		STX3_MOUSE (46-298): 1.65e-49: 168: 15.97
+	Mm
		936823 STXB2_MOUSE (2-560): 3.46e-175: 509: 19.90		STX4_MOUSE (66-318): 2.69e-48: 165: 18.49
+	Hs
		1030144 STXB2_HUMAN (2-560): 2.53e-172: 502: 19.39		STX3_HUMAN (46-298): 8.42e-51: 171: 16.35
+	Rn
		996532 STXB2_RAT (2-560): 3.99e-173: 504: 20.20		STX3_RAT (46-298): 1.03e-49: 168: 15.97
+	Hs
		901776 STXB1_HUMAN (2-566): 7.31e-170: 496: 18.91		STX4_HUMAN (41-318): 8.28e-49: 166: 18.90
+	Hs
		269420 STXB2_HUMAN (2-560): 2.53e-172: 502: 19.39		STX11_HUMAN (37-308): 2.87e-45: 157: 10.88
+	Hs
		269405 STXB1_HUMAN (2-566): 7.31e-170: 496: 18.91		STX11_HUMAN (37-308): 2.87e-45: 157: 10.88