Protein: NPY2R
Neuropeptide Y receptor type 2 (NPY2-R) (NPY-Y2 receptor) (Y2 receptor)

Gene: NPY2R
Organism: Homo sapiens
Interactions: 66
UniProt ID: P49146

Gene Ontology (top 5):
GO:0001601 - peptide YY receptor activity
GO:0001662 - behavioral fear response
GO:0002793 - positive regulation of peptide secretion
GO:0003151 - outflow tract morphogenesis
GO:0003214 - cardiac left ventricle morphogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

755533

TTK
Dual specificity protein kinase TTK

2

4

High-throughput

0.726

High

879810

DMXL2
DmX-like protein 2

2

5

High-throughput

0.726

High

777652

VGFR3
Vascular endothelial growth factor receptor 3

2

1

High-throughput

0.628

High

839201

MTOR
Serine/threonine-protein kinase mTOR

2

19

High-throughput

0.628

High

879808

EXOC6
Exocyst complex component 6

2

1

High-throughput

0.628

High

879809

CIP2A
Protein CIP2A

2

2

High-throughput

0.628

High

377339

NPY
Pro-neuropeptide Y [Cleaved into: Neuropeptide Y

1

3

Small-scale

0.618

High

879780

PRAME
Melanoma antigen preferentially expressed in tumors

2

0

High-throughput

0.602

High

552770

TPR
Nucleoprotein TPR

3

1

High-throughput

0.593

High

67363

RTL8C
Retrotransposon Gag-like protein 8C

2

2

High-throughput

0.574

High

137201

EXOC5
Exocyst complex component 5

2

1

High-throughput

0.574

High

173680

BTAF1
TATA-binding protein-associated factor 172

2

2

High-throughput

0.574

High

187486

FANCA
Fanconi anemia group A protein

2

2

High-throughput

0.574

High

228071

PM34
Peroxisomal membrane protein PMP34

2

11

High-throughput

0.574

High

273172

CAND2
Cullin-associated NEDD8-dissociated protein 2

2

6

High-throughput

0.574

High

318124

IPO13
Importin-13

2

10

High-throughput

0.574

High

843374

HD
Huntingtin

2

1

High-throughput

0.574

High

879782

ATM
Serine-protein kinase ATM

2

8

High-throughput

0.574

High

879783

COG2
Conserved oligomeric Golgi complex subunit 2

2

2

High-throughput

0.574

High

879784

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

2

6

High-throughput

0.574

High

879787

ORML2
ORM1-like protein 2

2

1

High-throughput

0.574

High

879788

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

2

6

High-throughput

0.574

High

879789

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

2

1

High-throughput

0.574

High

879790

SYRM
Probable arginine--tRNA ligase, mitochondrial

2

2

High-throughput

0.574

High

879791

S35F1
Solute carrier family 35 member F1

2

1

High-throughput

0.574

High

879792

BIG3
Brefeldin A-inhibited guanine nucleotide-exchange protein 3

2

3

High-throughput

0.574

High

879793

ECM29
Proteasome adapter and scaffold protein ECM29

2

8

High-throughput

0.574

High

879794

ACD10
Acyl-CoA dehydrogenase family member 10

2

2

High-throughput

0.574

High

879795

MZT2B
Mitotic-spindle organizing protein 2B

2

2

High-throughput

0.574

High

879797

INT5
Integrator complex subunit 5

2

1

High-throughput

0.574

High

879798

MMS22
Protein MMS22-like

2

1

High-throughput

0.574

High

879799

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

2

6

High-throughput

0.574

High

879801

ADCK1
AarF domain-containing protein kinase 1

2

5

High-throughput

0.574

High

879806

INT1
Integrator complex subunit 1

2

5

High-throughput

0.574

High

879811

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

2

3

High-throughput

0.574

High

879814

RUSF1
RUS family member 1

2

1

High-throughput

0.574

High

879816

GCP2
Gamma-tubulin complex component 2

2

7

High-throughput

0.574

High

879817

5NT1A
Cytosolic 5'-nucleotidase 1A

2

1

High-throughput

0.574

High

879819

NOCT
Nocturnin

2

1

High-throughput

0.574

High

879820

COG6
Conserved oligomeric Golgi complex subunit 6

2

1

High-throughput

0.574

High

879823

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

2

5

High-throughput

0.574

High

518437

PYY
Peptide YY

1

3

Small-scale

0.553

High

839439

PI4KA
Phosphatidylinositol 4-kinase alpha

2

8

High-throughput

0.552

High

879815

XPO6
Exportin-6

1

2

High-throughput

0.536

High

879786

Q4LE69
Phosphatidylinositol 4-kinase alpha

2

7

High-throughput

0.533

High

879805

EXOC8
Exocyst complex component 8

1

0

High-throughput

0.513

High

172575

XPO1
Exportin-1

1

15

High-throughput

0.489

High

245441

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

2

High-throughput

0.489

High

847384

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

879781

PRKDC
DNA-dependent protein kinase catalytic subunit

1

8

High-throughput

0.489

High

879785

PDK1
[Pyruvate dehydrogenase

1

2

High-throughput

0.489

High

879796

MTFR2
Mitochondrial fission regulator 2

1

1

High-throughput

0.489

High

879800

MON2
Protein MON2 homolog

1

5

High-throughput

0.489

High

879802

DAAF5
Dynein axonemal assembly factor 5

1

2

High-throughput

0.489

High

879812

GCN1
Stalled ribosome sensor GCN1

1

10

High-throughput

0.489

High

879818

COG4
Conserved oligomeric Golgi complex subunit 4

1

2

High-throughput

0.489

High

879822

TELO2
Telomere length regulation protein TEL2 homolog

1

2

High-throughput

0.489

High

879804

TARG1
Trafficking regulator of GLUT4 1

1

5

High-throughput

0.481

High

63645

A5PKU2
TUSC5 protein

1

5

High-throughput

0.470

High

317810

LTN1
E3 ubiquitin-protein ligase listerin

2

0

High-throughput

0.328

High

649873

ADRO
NADPH:adrenodoxin oxidoreductase, mitochondrial

2

0

High-throughput

0.328

High

879807

SIMC1
SUMO-interacting motif-containing protein 1

2

0

High-throughput

0.328

High

879813

EVI5L
EVI5-like protein

2

0

High-throughput

0.328

High

879803

TPPC5
Trafficking protein particle complex subunit 5

1

0

High-throughput

0.279

Low

879821

TIM16
Mitochondrial import inner membrane translocase subunit TIM16

1

0

High-throughput

0.279

Low

697035

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025