HitPredict

Interactor 1: TYOBP (O54885)
TYRO protein tyrosine kinase-binding protein (DNAX-activation protein 12) (Killer-activating receptor-associated protein) (KAR-associated protein)
Gene: Tyrobp

Interactor 2: TREM3 (Q9JKE1)
Triggering receptor expressed on myeloid cells 3 (TREM-3)
Gene: TREM3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11754004
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 114 Mm			1 183
+	Mm
		222481 TYOBP_MOUSE (1-114): 2.67e-69: 204: 100.00		CLM4_MOUSE (2-135): 8.65e-35: 123: 21.43
+	Hs
		217362 TYOBP_HUMAN (1-114): 7.88e-57: 173: 73.04		TREM1_HUMAN (1-133): 1e-42: 144: 36.77
+	Hs
		217366 TYOBP_HUMAN (1-114): 7.88e-57: 173: 73.04		TREM2_HUMAN (1-129): 6.13e-38: 131: 23.66
+	Hs
		217292 TYOBP_HUMAN (1-114): 7.88e-57: 173: 73.04		NCTR2_HUMAN (14-131): 9.68e-37: 130: 24.58
+	Hs
		217311 TYOBP_HUMAN (1-114): 7.88e-57: 173: 73.04		CLM6_HUMAN (9-115): 6.74e-37: 129: 23.36
+	Hs
		66493 TYOBP_HUMAN (1-114): 7.88e-57: 173: 73.04		CLM7_HUMAN (16-118): 6.18e-37: 128: 20.39
+	Mm
		222482 TYOBP_MOUSE (1-114): 2.67e-69: 204: 100.00		Q8BNV8_MOUSE (15-128): 1.2e-22: 92.1: 22.81
+	Hs
		3044 TYOBP_HUMAN (1-114): 7.88e-57: 173: 73.04		CD3CH_HUMAN (9-112): 2.15e-34: 121: 25.96
+	Hs
		217328 TYOBP_HUMAN (1-114): 7.88e-57: 173: 73.04		CLM5_HUMAN (20-138): 1.43e-33: 119: 19.33