Protein: KINH
Kinesin-1 heavy chain (Conventional kinesin heavy chain) (Ubiquitous kinesin heavy chain) (UKHC)

Gene: KINH, KIF5B
Organism: Homo sapiens
Interactions: 239
UniProt ID: P33176

Gene Ontology (top 5):
GO:0003777 - microtubule motor activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

244135

KIF5C
Kinesin heavy chain isoform 5C

5

16

Small-scale

0.906

High

749905

KIF5A
Kinesin heavy chain isoform 5A

4

16

High-throughput

0.886

High

749859

KINH
Kinesin-1 heavy chain

3

16

Small-scale

0.861

High

749903

KLC1
Kinesin light chain 1

11

20

Small-scale

0.756

High

749895

1433Z
14-3-3 protein zeta/delta

8

20

Small-scale

0.748

High

690771

1433T
14-3-3 protein theta

7

20

High-throughput

0.744

High

729639

1433B
14-3-3 protein beta/alpha

7

20

High-throughput

0.744

High

749899

1433F
14-3-3 protein eta

6

20

Small-scale

0.737

High

749889

1433G
14-3-3 protein gamma

6

20

High-throughput

0.736

High

750000

KLC2
Kinesin light chain 2

5

20

Small-scale

0.714

High

749945

TBA1A
Tubulin alpha-1A chain

1

7

High-throughput

0.691

High

750022

KDIS
Kinase D-interacting substrate of 220 kDa

1

3

High-throughput

0.691

High

749935

KLC3
Kinesin light chain 3

3

20

High-throughput

0.675

High

171801

AZIN1
Antizyme inhibitor 1

3

1

High-throughput

0.667

High

244833

TRAK2
Trafficking kinesin-binding protein 2

3

20

High-throughput

0.667

High

749919

TRIP6
Thyroid receptor-interacting protein 6

3

4

High-throughput

0.667

High

749967

NUP43
Nucleoporin Nup43

3

4

High-throughput

0.667

High

749891

1433E
14-3-3 protein epsilon

3

7

High-throughput

0.656

High

725478

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

3

3

High-throughput

0.654

High

749982

DTBP1
Dysbindin

3

2

High-throughput

0.650

High

749989

MA7D2
MAP7 domain-containing protein 2

2

4

High-throughput

0.628

High

750011

KLC4
Kinesin light chain 4

2

20

High-throughput

0.628

High

750013

EXOC1
Exocyst complex component 1

2

4

High-throughput

0.628

High

750024

TRAK1
Trafficking kinesin-binding protein 1

3

18

Small-scale

0.624

High

749993

FYCO1
FYVE and coiled-coil domain-containing protein 1

2

5

Small-scale

0.621

High

749917

KIF14
Kinesin-like protein KIF14

1

17

High-throughput

0.618

High

749970

ASB11
Ankyrin repeat and SOCS box protein 11

1

6

High-throughput

0.618

High

749952

NAA40
N-alpha-acetyltransferase 40

2

2

High-throughput

0.611

High

749983

AURKB
Aurora kinase B

2

2

High-throughput

0.611

High

749964

SYNE4
Nesprin-4

3

2

High-throughput

0.609

High

750030

KPTN
KICSTOR complex protein kaptin

3

1

High-throughput

0.609

High

725356

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

3

High-throughput

0.606

High

749979

GCC1
GRIP and coiled-coil domain-containing protein 1

2

3

High-throughput

0.606

High

730412

1433S
14-3-3 protein sigma

2

20

High-throughput

0.601

High

749864

NUP62
Nuclear pore glycoprotein p62

2

6

High-throughput

0.601

High

749969

BRK1
Protein BRICK1

2

3

High-throughput

0.601

High

749875

GSK3B
Glycogen synthase kinase-3 beta

2

4

High-throughput

0.600

High

749977

ZBT8A
Zinc finger and BTB domain-containing protein 8A

3

11

High-throughput

0.597

High

749991

CDC5L
Cell division cycle 5-like protein

2

6

High-throughput

0.590

High

240883

PRKN
E3 ubiquitin-protein ligase parkin

2

7

High-throughput

0.584

High

345429

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

8

High-throughput

0.584

High

536605

HSP7C
Heat shock cognate 71 kDa protein

2

5

High-throughput

0.584

High

749865

SYUA
Alpha-synuclein

2

2

Small-scale

0.584

High

749871

TCPE
T-complex protein 1 subunit epsilon

2

7

High-throughput

0.584

High

749874

RBP2
E3 SUMO-protein ligase RanBP2

2

5

Small-scale

0.584

High

749950

HUWE1
E3 ubiquitin-protein ligase HUWE1

2

6

High-throughput

0.584

High

269152

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

336629

BAG4
BAG family molecular chaperone regulator 4

2

0

High-throughput

0.580

High

749898

CDR2
Cerebellar degeneration-related protein 2

2

0

High-throughput

0.580

High

553739

MYCL
Protein L-Myc

2

9

High-throughput

0.574

High

750025

COG6
Conserved oligomeric Golgi complex subunit 6

2

2

High-throughput

0.574

High

563297

CFTR
Cystic fibrosis transmembrane conductance regulator

2

2

High-throughput

0.571

High

749893

RPB7
DNA-directed RNA polymerase II subunit RPB7

2

1

High-throughput

0.553

High

749896

PO6F2
POU domain, class 6, transcription factor 2

2

3

High-throughput

0.553

High

749911

FHL2
Four and a half LIM domains protein 2

2

1

High-throughput

0.553

High

749921

EZH2
Histone-lysine N-methyltransferase EZH2

2

4

High-throughput

0.549

High

750016

S53A1
Solute carrier family 53 member 1

2

1

High-throughput

0.549

High

668514

APC
Adenomatous polyposis coli protein

1

8

High-throughput

0.541

High

750027

RPGF2
Rap guanine nucleotide exchange factor 2

1

3

High-throughput

0.541

High

168640

CSKP
Peripheral plasma membrane protein CASK

1

18

High-throughput

0.536

High

185469

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

6

High-throughput

0.536

High

244230

NUAK1
NUAK family SNF1-like kinase 1

1

4

High-throughput

0.536

High

278248

NCOR1
Nuclear receptor corepressor 1

1

4

High-throughput

0.536

High

447687

TPM3
Tropomyosin alpha-3 chain

1

3

High-throughput

0.536

High

549540

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

3

High-throughput

0.536

High

700814

PIT1
Pituitary-specific positive transcription factor 1

1

3

High-throughput

0.536

High

749861

BMI1
Polycomb complex protein BMI-1

1

10

High-throughput

0.536

High

749879

HSP72
Heat shock-related 70 kDa protein 2

1

5

High-throughput

0.536

High

749882

PSA
Puromycin-sensitive aminopeptidase

1

1

High-throughput

0.536

High

749900

KPCZ
Protein kinase C zeta type

1

3

High-throughput

0.536

High

749908

SQSTM
Sequestosome-1

1

4

High-throughput

0.536

High

749922

IF16
Gamma-interferon-inducible protein 16

1

2

High-throughput

0.536

High

749946

MARK2
Serine/threonine-protein kinase MARK2

1

3

High-throughput

0.536

High

749958

HOME1
Homer protein homolog 1

1

2

High-throughput

0.536

High

749959

MYLK4
Myosin light chain kinase family member 4

1

1

High-throughput

0.536

High

749962

SPART
Spartin

1

5

Small-scale

0.536

High

749968

NEK7
Serine/threonine-protein kinase Nek7

1

4

High-throughput

0.536

High

749980

HVCN1
Voltage-gated hydrogen channel 1

1

1

High-throughput

0.536

High

123998

SNP23
Synaptosomal-associated protein 23

1

3

Small-scale

0.527

High

749884

SNP25
Synaptosomal-associated protein 25

1

3

Small-scale

0.527

High

640780

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

1

High-throughput

0.515

High

656051

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

1

High-throughput

0.515

High

361140

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.513

High

749863

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.513

High

750003

SG196
Protein O-mannose kinase

1

0

High-throughput

0.513

High

750005

S38AA
Solute carrier family 38 member 10

1

0

High-throughput

0.513

High

262368

DTNB
Dystrobrevin beta

1

5

Small-scale

0.501

High

302042

SEGN
Secretagogin

1

5

Small-scale

0.501

High

749887

SUMO2
Small ubiquitin-related modifier 2

1

4

High-throughput

0.501

High

750028

MYO5A
Unconventional myosin-Va

1

2

Small-scale

0.501

High

648097

NDKB
Nucleoside diphosphate kinase B

1

0

High-throughput

0.493

High

749975

NDRG1
Protein NDRG1

1

0

Small-scale

0.493

High

323968

CSTN1
Calsyntenin-1

1

4

High-throughput

0.489

High

706073

S10A2
Protein S100-A2

1

5

High-throughput

0.489

High

749923

INSY1
Inhibitory synaptic factor 1

1

4

High-throughput

0.489

High

749938

NHS
Actin remodeling regulator NHS

1

1

High-throughput

0.489

High

749961

SYCE1
Synaptonemal complex central element protein 1

1

2

High-throughput

0.489

High

749876

MEOX2
Homeobox protein MOX-2

1

6

High-throughput

0.481

High

749927

ECM29
Proteasome adapter and scaffold protein ECM29

1

2

Small-scale

0.481

High

749954

TAXB1
Tax1-binding protein 1

1

10

High-throughput

0.481

High

749963

VPS52
Vacuolar protein sorting-associated protein 52 homolog

1

6

High-throughput

0.481

High

239542

MED14
Mediator of RNA polymerase II transcription subunit 14

1

4

High-throughput

0.479

High

247240

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

5

High-throughput

0.479

High

276280

HMMR
Hyaluronan mediated motility receptor

1

5

High-throughput

0.479

High

294831

BCAR3
Breast cancer anti-estrogen resistance protein 3

1

3

High-throughput

0.479

High

324581

HEXI1
Protein HEXIM1

1

2

High-throughput

0.479

High

371299

MYC
Myc proto-oncogene protein

1

9

High-throughput

0.479

High

411454

NTRK1
High affinity nerve growth factor receptor

1

13

High-throughput

0.479

High

413284

P53
Cellular tumor antigen p53

1

3

High-throughput

0.479

High

534701

BIP
Endoplasmic reticulum chaperone BiP

1

8

High-throughput

0.479

High

535925

MYH3
Myosin-3

1

1

High-throughput

0.479

High

552760

TPR
Nucleoprotein TPR

1

4

High-throughput

0.479

High

555902

CADH1
Cadherin-1

1

3

High-throughput

0.479

High

606319

CEBPB
CCAAT/enhancer-binding protein beta

1

4

High-throughput

0.479

High

623141

RO52
E3 ubiquitin-protein ligase TRIM21

1

7

High-throughput

0.479

High

642656

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

5

High-throughput

0.479

High

699611

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

6

High-throughput

0.479

High

713895

PML
Protein PML

1

18

High-throughput

0.479

High

749860

CTNB1
Catenin beta-1

1

5

High-throughput

0.479

High

749867

BRCA1
Breast cancer type 1 susceptibility protein

1

7

High-throughput

0.479

High

749868

VHL
von Hippel-Lindau disease tumor suppressor

1

5

High-throughput

0.479

High

749869

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

749870

YAP1
Transcriptional coactivator YAP1

1

14

High-throughput

0.479

High

749872

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

1

High-throughput

0.479

High

749877

CDK9
Cyclin-dependent kinase 9

1

3

High-throughput

0.479

High

749883

HDAC4
Histone deacetylase 4

1

8

High-throughput

0.479

High

749885

ABCE1
ATP-binding cassette sub-family E member 1

1

1

High-throughput

0.479

High

749886

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

1

High-throughput

0.479

High

749890

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

749892

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

749894

RB11A
Ras-related protein Rab-11A

1

2

High-throughput

0.479

High

749897

VIGLN
Vigilin

1

6

High-throughput

0.479

High

749904

EP300
Histone acetyltransferase p300

1

7

High-throughput

0.479

High

749907

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

749909

CUL3
Cullin-3

1

7

High-throughput

0.479

High

749910

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

6

High-throughput

0.479

High

749912

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

16

Small-scale

0.479

High

749913

CUL7
Cullin-7

1

4

High-throughput

0.479

High

749915

TNIP1
TNFAIP3-interacting protein 1

1

6

High-throughput

0.479

High

749916

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.479

High

749918

PCBP1
Poly(rC)-binding protein 1

1

4

Small-scale

0.479

High

749920

SMAD2
Mothers against decapentaplegic homolog 2

1

1

High-throughput

0.479

High

749931

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

749934

IFIX
Pyrin and HIN domain-containing protein 1

1

2

High-throughput

0.479

High

749937

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.479

High

749941

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

5

High-throughput

0.479

High

749942

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

749943

MOB3C
MOB kinase activator 3C

1

1

High-throughput

0.479

High

749948

TICRR
Treslin

1

2

High-throughput

0.479

High

749951

ZN598
E3 ubiquitin-protein ligase ZNF598

1

2

High-throughput

0.479

High

749955

HOOK3
Protein Hook homolog 3

1

9

High-throughput

0.479

High

749960

LMTK2
Serine/threonine-protein kinase LMTK2

1

15

High-throughput

0.479

High

749965

RHG24
Rho GTPase-activating protein 24

1

3

High-throughput

0.479

High

749966

RUSC2
AP-4 complex accessory subunit RUSC2

1

2

Small-scale

0.479

High

749971

RFFL
E3 ubiquitin-protein ligase rififylin

1

3

Small-scale

0.479

High

749972

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

3

High-throughput

0.479

High

749973

TOPB1
DNA topoisomerase 2-binding protein 1

1

1

High-throughput

0.479

High

749974

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

749976

ESR2
Estrogen receptor beta

1

9

High-throughput

0.479

High

749978

ARMC5
Armadillo repeat-containing protein 5

1

5

High-throughput

0.479

High

749992

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.479

High

749995

RUSC1
AP-4 complex accessory subunit RUSC1

1

2

Small-scale

0.479

High

749999

WWTR1
WW domain-containing transcription regulator protein 1

1

11

High-throughput

0.479

High

750001

PKHA4
Pleckstrin homology domain-containing family A member 4

1

17

High-throughput

0.479

High

750007

MED4
Mediator of RNA polymerase II transcription subunit 4

1

4

High-throughput

0.479

High

750008

ANLN
Anillin

1

4

High-throughput

0.479

High

750009

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

3

High-throughput

0.479

High

750018

KS6B2
Ribosomal protein S6 kinase beta-2

1

2

High-throughput

0.479

High

750019

ZRAN1
Ubiquitin thioesterase ZRANB1

1

15

High-throughput

0.479

High

750020

ACHA9
Neuronal acetylcholine receptor subunit alpha-9

1

2

High-throughput

0.479

High

750021

HOOK1
Protein Hook homolog 1

1

8

High-throughput

0.479

High

750026

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

1

High-throughput

0.479

High

750031

NEMO
NF-kappa-B essential modulator

1

5

High-throughput

0.479

High

749932

Q6FHY5
MEOX2 protein

1

5

High-throughput

0.470

High

158127

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.458

High

714766

EF1D
Elongation factor 1-delta

1

0

High-throughput

0.458

High

749866

ETFB
Electron transfer flavoprotein subunit beta

1

0

High-throughput

0.458

High

749914

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

749924

LETM2
LETM1 domain-containing protein LETM2, mitochondrial

1

0

High-throughput

0.458

High

749940

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.458

High

749956

NAL10
NACHT, LRR and PYD domains-containing protein 10

1

0

High-throughput

0.458

High

749987

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

749990

CNN2
Calponin-2

1

0

High-throughput

0.458

High

750004

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

750012

ABCF3
ATP-binding cassette sub-family F member 3

1

0

High-throughput

0.458

High

749902

FMR1
Fragile X messenger ribonucleoprotein 1

1

16

High-throughput

0.457

High

62457

S35F4
Solute carrier family 35 member F4

1

1

High-throughput

0.445

High

91641

C9JC32
Trafficking kinesin protein 1

1

19

High-throughput

0.445

High

107390

F8W6L3
Kinesin light chain

1

20

High-throughput

0.445

High

529200

TAU
Microtubule-associated protein tau

1

13

High-throughput

0.445

High

653155

HEMH
Ferrochelatase, mitochondrial

1

1

High-throughput

0.445

High

749880

S12A3
Solute carrier family 12 member 3

1

1

High-throughput

0.445

High

749881

TERA
Transitional endoplasmic reticulum ATPase

1

7

High-throughput

0.445

High

749925

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

6

High-throughput

0.445

High

749930

CP135
Centrosomal protein of 135 kDa

1

4

High-throughput

0.445

High

749933

PKHA7
Pleckstrin homology domain-containing family A member 7

1

19

High-throughput

0.445

High

749936

CSAG1
Chondrosarcoma-associated gene 1 protein

1

2

High-throughput

0.445

High

749985

NEUL4
Neuralized-like protein 4

1

1

High-throughput

0.445

High

749988

CEP63
Centrosomal protein of 63 kDa

1

6

High-throughput

0.445

High

749998

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.445

High

749984

CC136
Coiled-coil domain-containing protein 136

1

4

High-throughput

0.439

High

91796

ZN878
Zinc finger protein 878

1

1

High-throughput

0.437

High

105441

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

176032

KDM6B
Lysine-specific demethylase 6B

1

3

Small-scale

0.437

High

217885

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.437

High

259518

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.437

High

588023

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.437

High

694737

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

7

High-throughput

0.437

High

749862

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

749888

WDR5
WD repeat-containing protein 5

1

3

High-throughput

0.437

High

749901

FHI1A
FHF complex subunit HOOK-interacting protein 1A

1

9

High-throughput

0.437

High

749906

TIF1B
Transcription intermediary factor 1-beta

1

17

High-throughput

0.437

High

749929

FHI2A
FHF complex subunit HOOK interacting protein 2A

1

9

High-throughput

0.437

High

749939

LMBRL
Protein LMBR1L

1

2

High-throughput

0.437

High

749947

MEPCE
7SK snRNA methylphosphate capping enzyme

1

1

High-throughput

0.437

High

749949

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.437

High

749953

FHI2B
FHF complex subunit HOOK-interacting protein 2B

1

9

High-throughput

0.437

High

749997

ZFHX2
Zinc finger homeobox protein 2

1

1

High-throughput

0.437

High

750006

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

2

High-throughput

0.437

High

750017

TR10D
Tumor necrosis factor receptor superfamily member 10D

1

1

High-throughput

0.437

High

750023

TRI33
E3 ubiquitin-protein ligase TRIM33

1

17

High-throughput

0.437

High

749957

S2611
Sodium-independent sulfate anion transporter

1

0

High-throughput

0.426

High

749986

S45A3
Solute carrier family 45 member 3

1

0

High-throughput

0.426

High

750015

UVRAG
UV radiation resistance-associated gene protein

1

0

High-throughput

0.426

High

749873

CEBPA
CCAAT/enhancer-binding protein alpha

1

4

High-throughput

0.408

High

261107

NSMA
Sphingomyelin phosphodiesterase 2

1

1

High-throughput

0.407

High

429385

JUN
Transcription factor Jun

1

3

High-throughput

0.407

High

749944

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

5

High-throughput

0.407

High

750002

VIAAT
Vesicular inhibitory amino acid transporter

1

2

High-throughput

0.407

High

750029

CSAG2
Chondrosarcoma-associated gene 2/3 protein

1

2

High-throughput

0.407

High

749981

SGF29
SAGA-associated factor 29

4

0

High-throughput

0.360

High

749878

LBX1
Transcription factor LBX1

2

0

High-throughput

0.316

High

749926

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.279

Low

749928

USPL1
SUMO-specific isopeptidase USPL1

1

0

High-throughput

0.279

Low

749996

FOXQ1
Forkhead box protein Q1

1

0

High-throughput

0.279

Low

749994

TRMO
tRNA

1

0

High-throughput

0.249

Low

750010

SIA7A
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1

1

0

High-throughput

0.249

Low

750014

PD1L1
Programmed cell death 1 ligand 1

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025